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Combining irinotecan and cetuximab is effective for some metastatic colorectal cancer patients but often causes manageable skin issues.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

More research is needed to understand the genetic causes of Alopecia areata to develop better treatments.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Scalp cooling effectively reduces hair loss from chemotherapy.

Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.

The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.

Krt15+ cells in the mouse intestine resist radiation and can start tumors.

The plant hormone auxin activates the TOR pathway, affecting gene expression related to growth and cell size.

Certain genetic variations in the FST gene are linked to better wool quality in Chinese Merino sheep.

Clim proteins are essential for maintaining healthy corneas and hair follicles.

Genetic discoveries are leading to new treatments for alopecia areata.

The guidelines help doctors manage skin problems from certain cancer treatments to improve patients' lives.

HB-EGF boosts the hair growth ability of stem cells, making it a potential hair loss treatment.

KCNQ potassium channels help control the sensitivity of touch receptors in the skin.

Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.

The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.

Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.

EGFR helps control how hair grows and forms without needing p53 protein.

SOX9 is essential for the development of various organs and hair follicles.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

The local environment is crucial for cell development in the tongue.

Inhibiting Zyxin may help treat androgenetic alopecia by promoting hair growth.