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The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.

The document concludes that various signaling pathways and genetic factors are crucial for chicken feather development, affecting poultry quality.

Different types of stem cells and their environments are key to skin repair and maintenance.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.

The study identified key genes and pathways linked to hair disorders, aiding precision medicine.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Gene differences found in hair follicles linked to male baldness.

EGFR inhibitors can cause various skin issues during cancer treatment, and managing these is important for patient care.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

Dermal factors are crucial in regulating melanin production in skin.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.

Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

Ectoin helps prevent cortisone-induced skin problems and supports skin health.

The exact identity of skin stem cells and how skin cells differentiate is not fully known.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

EGF controls hair growth by regulating hair follicles' growth phases.

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.

Targeted cancer therapies often cause serious skin problems that need careful management.