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    Glossary Epristeride

    Epristeride is a selective inhibitor of type II 5-alpha-reductase, an enzyme that converts testosterone into dihydrotestosterone (DHT), a hormone closely linked to androgenetic alopecia (male and female pattern hair loss). By reducing DHT levels, epristeride aims to slow down hair loss and promote hair regrowth in individuals affected by this condition. Its relevance lies in its potential as a therapeutic option for hair loss, distinguishing it from other treatments by its targeted action on the hormonal pathway involved in hair follicle miniaturization.

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    Research 30 of 43

    1. Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor Bioorganic & Medicinal Chemistry Letters · 2010 · 18 citations
    2. Effection of Epristeride and Finasteride on Spermatogenesis in Male Rats Yaoxue jinzhan · 2002 · 1 citations
    3. Analysis of metabolic characteristics of epristeride in zebrafish based on LC-Q-TOF MS and its potential applications in doping control RSC Advances · 2026
    4. Identification of Metabolites for the Novel 5α‐Reductase Inhibitor Epristeride In Vitro and Its Potential Impact on Doping Testing Drug Testing and Analysis · 2025
    5. ChemInform Abstract: Discovery of a Novel Hybrid from Finasteride and Epristeride as 5α‐Reductase Inhibitor. ChemInform · 2011
    6. An overview on 5α-reductase inhibitors Steroids · 2009 · 219 citations
    7. Chapter 23. Therapeutic Control of Androgen Action Annual Reports in Medicinal Chemistry · 1994 · 7 citations
    8. 5α-Reductase Inhibitors Do Not Prevent the Development and Progression of Urothelial Cancer: In Vitro Evidence Bladder cancer · 2020 · 3 citations
    9. Market Analysis of 5α-Reductase Inhibitor Zhongguo yaofang · 2006
    10. Screen steroid 5 alpha-reductase inhibitors in vitro by high performance liquid chromatography Fuzhou daxue xuebao. Ziran kexue ban · 2005
    11. New Synthesis of Methyl 3β-Hydroxy-5-androstene-17β-carboxylate Chinese Journal of Pharmaceuticals · 2002
    12. Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2 Steroids · 2017 · 8 citations
    13. FCE 28260, a new 5α-reductase inhibitor: In vitro and in vivo effects The Journal of Steroid Biochemistry and Molecular Biology · 1996 · 17 citations
    14. Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase Bioorganic & Medicinal Chemistry · 1997 · 5 citations
    15. Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives 2002 · 233 citations
    16. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011 · 218 citations
    17. Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases The Journal of Steroid Biochemistry and Molecular Biology · 2013 · 51 citations
    18. PNU 157706, a novel dual type I and II5α-reductase inhibitor The Journal of Steroid Biochemistry and Molecular Biology · 1998 · 42 citations
    19. Evaluation of 5α-reductase inhibitory activity of certain herbs useful as antiandrogens Andrologia · 2013 · 33 citations
    20. Effects of Short-Term Finasteride on Apoptotic Factors and Androgen Receptors in Prostate Cancer Cells The Journal of Urology · 2008 · 25 citations
    21. Abietic Acid from Resina Pini of Pinus Species as a Testosterone 5.ALPHA.-Reductase Inhibitor JOURNAL OF HEALTH SCIENCE · 2010 · 21 citations
    22. Novel inhibitors of 5α-reductase Expert Opinion on Therapeutic Patents · 2002 · 20 citations
    23. Geranylated Coumarins From Thai Medicinal Plant Mammea siamensis With Testosterone 5α-Reductase Inhibitory Activity Frontiers in Chemistry · 2020 · 17 citations
    24. 5α-Reductase Inhibitors, Chemical and Clinical Models Steroids · 1998 · 17 citations
    25. Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens Journal of Medicinal Chemistry · 1995 · 12 citations
    26. Treatment of androgen excess in females: Yesterday, today and tomorrow Gynecological Endocrinology · 1997 · 9 citations
    27. Pharmacological Options for Treatment of Hyperandrogenic Disorders Mini-reviews in Medicinal Chemistry · 2009 · 6 citations
    28. Do 5α-Reductase Inhibitors Raise Circulating Serum Testosterone Levels? A Comprehensive Review and Meta-Analysis to Explaining Paradoxical Results Sexual Medicine Reviews · 2018 · 5 citations
    29. Determination of rat 5α-reductase type 1 isozyme activity and its inhibition by novel steroidal oxazolines Acta Biologica Hungarica · 2010 · 4 citations
    30. Clinical use of 5α-reductase inhibitors Cambridge University Press eBooks · 2001 · 3 citations