28 citations
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January 2015 in “Journal of Cell Science” In this study, PINCH-1 gene loss in mouse epidermis led to detachment from the basement membrane, thickened skin, and hair loss, with findings suggesting PINCH-1 plays a role in keratinocyte adhesion through both ILK and EPLIN pathways.
4 citations
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July 2016 in “Dermatologic Surgery” In this study, the duration of epinephrine-induced vasoconstriction in scalp tissue increased with concentration and was longer at the frontotemporal junction compared to the midfrontal area, significantly so at the highest concentration used.
This study reports two cases of severe alopecia areata showing seemingly permanent hair regrowth with a modified triamcinolone acetonide regimen involving epinephrine, and suggests a potential role for epinephrine in enhancing treatment efficacy.
October 1933 in “Experimental Biology and Medicine” In this study, subcutaneous injections of epinephrine in rats led to skin changes ranging from hair loss to necrosis, suggesting these effects were due to the epinephrine itself.
May 2022 in “Endocrine Abstracts” Finasteride may cause sexual dysfunction by reducing epinephrine levels.
November 2001 in “Oncology Times” The committee unanimously voted against recommending approval of the injectable cisplatin/epinephrine gel IntraDose for certain head and neck cancer patients, citing insufficient clinical benefit and concerns about toxicity in this study.
January 2022 in “UiTM Institutional Repositories (Universiti Teknologi MARA)” In this study, the application of Enriched and Enhanced Virgin Coconut Oil reportedly improved hair growth and reduced the appearance of scars in a teacher with cancer, suggesting benefits over typical post-chemotherapy recovery.
This study developed a three-dimensional model for studying hair follicle development, showing that immortalized dermal papilla cells retain certain differentiation activities and can induce tubule formation in vitro.
38 citations
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January 2014 in “International Journal of Endocrinology” This review highlights that children with adrenal disorders may experience neurological and psychiatric symptoms, with potential long-term cognitive and behavioral effects from excess glucocorticoids.
20 citations
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August 2017 in “Drug testing and analysis” This study used micro-segmental hair analysis to identify the day of drug intake and suggested differing uptake mechanisms for co-administered drugs based on their properties.
20 citations
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January 2006 in “Clinics in Plastic Surgery” This article discusses the benefits of tumescent surgery, such as reduced blood loss and pain control, but reports no new clinical findings.
16 citations
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May 1998 in “International Journal of Dermatology” This study found that elevated serum cortisol levels and other immunological changes are significantly involved in the active phases of psoriasis eruptions.
12 citations
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April 2020 in “Facial Plastic Surgery Clinics of North America” This article discusses potential complications in hair restoration surgery and emphasizes the importance of thorough planning and patient participation in reducing risks, but reports no new clinical findings.
4 citations
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June 2021 in “Basic and Clinical Neuroscience Journal” In this study, transplantation of rat hair follicle stem cells significantly improved sciatic nerve regeneration and muscle function in nerve-injured rats.
4 citations
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January 2012 in “Elsevier eBooks” The document concludes that various skin conditions have specific treatments, ranging from antihistamines for urticaria to surgery and medication for tumors and chronic skin diseases.
4 citations
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March 2002 in “Hair transplant forum international” This abstract discusses the challenges and considerations of hair restoration surgery related to the skin's rich neuro-vascular supply and does not report new clinical results.
3 citations
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January 2021 in “Skin appendage disorders” This study reports anagen hair loss four weeks after scalp surgeries, likely due to transient ischemia, and emphasizes the importance of informing patients about potential hair loss and recovery within three months.
2 citations
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April 2018 in “Journal of Cosmetic Dermatology” This study found that hair shaft exit angles in patients undergoing strip hair restoration increased after the tumescence injection and further increased after strip excision.
1 citations
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August 2023 in “Andrology” In this animal study, finasteride treatment altered testosterone metabolism in rat corpus cavernosum, linked to mechanisms of erectile dysfunction, but these changes were reversed after stopping the drug, suggesting post-treatment sexual side effects may relate more to central control dysfunction than peripheral issues.
1 citations
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September 2017 in “Dermatologic Surgery” The cephalic approach for nerve blocks is less painful than the anterior approach during hair restoration surgery.
May 2026 in “International Journal of Drug Delivery Technology” This study found that infiltrating dilute adrenaline into the recipient area during implanter-based FUE hair transplantation significantly reduced intraoperative bleeding, improving graft precision and visualization, without major safety concerns among the 50 patients observed.
May 2026 in “Nature Communications” In this study, researchers identified that keloid fibroblasts respond to neurotransmitters from catecholaminergic nerves by producing bone matrix proteins, mediated by β1-adrenergic receptor activation, leading to fibro-osseous reprogramming; blocking this signaling in a rodent model prevented the development of keloid-like pathology.
This study found that follicular unit extraction can be safely performed without bupivacaine and nerve blocks, using lignocaine with adrenaline as an effective anesthetic for patients with certain grades of androgenetic alopecia.
May 2021 in “Clinical Endoscopy” This study found that adding platelet-rich plasma to standard treatment reduced rebleeding in patients with peptic ulcer bleeding compared to additional epinephrine injections.
July 2020 in “Hair transplant forum international” This case report describes how nitroglycerin (sublingual) was used to prevent further scalp necrosis during hair restoration surgery, particularly in a patient experiencing early necrosis linked to local anesthetics with epinephrine.
This article reviews interventions for preventing chemotherapy-induced alopecia and highlights scalp cooling as the only currently effective method, while noting its limitations and other potential options without providing new results.
May 2013 in “Hair transplant forum international” The article discusses a complication that occurred during a follicular unit extraction hair restoration procedure, presenting an opportunity for the author to learn from the experience and reports no new research findings.
March 2000 in “Aesthetic Surgery Journal” This article discusses the art and technique of hair transplantation, noting the importance of donor hair density and improved hairline designs, and reports no new clinical results.
25 citations
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June 2020 in “Dermatology practical & conceptual” This study reviewed treatments for chemotherapy-induced hair loss, finding that scalp cooling is FDA-approved for prevention, while minoxidil and bimatoprost may aid post-chemotherapy regrowth. The authors emphasized tailored therapies and the potential utility of tools like trichoscopy and trichogram.
11 citations
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October 2011 in “Allergologia et immunopathologia” A girl with Netherton syndrome was able to eat wheat without allergies after a special treatment.