research Chemotherapy of Psoriasis and Other Skin Disorders with Oral Retinoids
Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.
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research Planar Cell Polarity Effector Gene Intu Regulates Cell Fate-Specific Differentiation of Keratinocytes Through the Primary Cilia
Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
research Hair Follicle Regeneration Suppresses Ras-Driven Oncogenic Growth
Hair follicle regeneration may slow tumor growth.
research Epimorphin Expression During Human Fetal Hair Follicle Development
Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
research Developmental Mechanisms Controlling Cell Fate Evolution
The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.
research Scratching the Surface of Skin Development
The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
research Fibroblast Heterogeneity: Implications for Human Disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Vitamin D Metabolism and Function in the Skin
Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
research Androgens and Human Hair Growth
Androgens can cause hair growth in some areas and hair loss on the scalp.
research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin
The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
research Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion
The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
research Endogenous Retinoids in the Hair Follicle and Sebaceous Gland
Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
research Systematic Analysis of Non-coding RNAs Involved in the Angora Rabbit Hair Follicle Cycle by RNA Sequencing
Non-coding RNAs play key roles in the hair growth cycle of Angora rabbits.
research Transformation of Amnion Epithelium into Skin and Hair Follicles
Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.
research Mechanism of TAp73 Inhibition by ΔNp63 and Structural Basis of p63/p73 Hetero-Tetramerization
ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.
research The ITGB6 Gene: Its Role in Experimental and Clinical Biology
The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.
research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research Retinoid Metabolism Is Altered in Human and Mouse Cicatricial Alopecia
Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
research Activation of the OVOL1-OVOL2 Axis in the Hair Bulb and Pilomatricoma
The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.
research Histogenesis of Keratoacanthoma: Histochemical and Immunohistochemical Study
Keratoacanthoma comes from hair follicle cells.
research The Role of P-Cadherin in Skin Biology and Pathology: Lessons from the Hair Follicle
P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
research The Preventive Effect of Vitamin D3 on Radiation-Induced Hair Toxicity in a Rat Model
Vitamin D3 may protect rat hair follicles from radiation damage.
research A Spontaneous Deletion Within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype
A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.
research Fetal Wound Healing Using a Genetically Modified Murine Model: The Contribution of P-Selectin
P-selectin is not the only factor that prevents scarring in fetal wound healing in mice.
research Characterization of a Mouse Scube3 Reporter Line
Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.
research Analysis of the Expression Pattern of the Carrier Protein Transthyretin and Its Receptor Megalin in the Human Scalp Skin and Hair Follicles: Hair Cycle-Associated Changes
The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.
research New Developments in Stem Cell Biology and Therapy: Meeting Report from the Working Group of the German Society for Hematology and Oncology
The meeting highlighted important advances in stem cell research and its potential for creating new medical treatments.
research New Insights Into Inflammatory Memory of Epidermal Stem Cells
Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
research Inherited Disorders of the Hair
The document explains the genetic causes and characteristics of inherited hair disorders.