research Matricellular Proteins in the Homeostasis, Regeneration, and Aging of Skin
Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
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research Risk and Benefit of CD133+ Progenitors
CD133+ progenitor cells have therapeutic potential for diabetic ulcers and heart attack recovery, with manageable risks.
research Feasibility of Repairing Skin Defects by VEGF165 Gene-Modified iPS-HFSCs Seeded on a 3D Printed Scaffold Containing Astragalus Polysaccharide
The new method using gene-modified stem cells and a 3D printed scaffold improved skin repair in mice.
research Regulatory T Cells Influence Hair Follicle Cycle and Stem Cell Activation
Immune cells called Treg cells are essential for hair growth and regeneration.
research Proceedings of the Ninth World Congress for Hair Research 2015
The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
research Strategies to Utilize iPS Cells for Hair Follicle Regeneration and the Treatment of Hair Loss Disorders
hiPSCs can help regenerate hair follicles and treat hair loss.
research Scarless Wound Healing: Finding the Right Cells and Signals
The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
research Generation of Skin Organoids: Potential Opportunities and Challenges
Skin organoids from stem cells could better mimic real skin but face challenges.
research Human Keratinocytes Derived from the Bulge Region of Hair Follicles Are Refractory to Differentiation
Hair follicle cells resist turning into skin cells.
research Keratin Function and Regulation in Tissue Homeostasis and Pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg-like Cells, and Common EGFR Somatic Mutations
Cutaneous Lymphadenoma is a unique skin tumor with specific protein markers and common gene mutations that may cause continuous cell growth.
research Hdac1 and Hdac2 Regulate the Quiescent State and Survival of Hair-Follicle Mesenchymal Niche
Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
research TLR9 Activation in Large Wound Induces Tissue Repair and Hair Follicle Regeneration via γδT Cells
Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
research Role of Bulge Cells in Wound Healing: Possible Implications for Hidradenitis Suppurativa
Hair follicle bulge cells are important for hair survival and help heal the skin after injury, which might be relevant for understanding hidradenitis suppurativa.
research Cell Fate Decisions: Emerging Roles for Metabolic Signals and Cell Morphology
Metabolic signals and cell shape influence how cells develop and change.
research Fetal Skin Wound Healing
Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
research Hydrogel from Acellular Porcine Adipose Tissue Accelerates Wound Healing by Inducing Intradermal Adipocyte Regeneration
A hydrogel made from pig fat helps wounds heal faster by regenerating skin fat cells.
research Deciphering Principles of Morphogenesis from Temporal and Spatial Patterns on the Integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
research Novel Insights Into the Pathways Regulating the Canine Hair Cycle and Their Deregulation in Alopecia X
The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
research Dietary Vitamin A Regulates Wingless-Related MMTV Integration Site Signaling to Alter the Hair Cycle
Eating vitamin A affects hair growth and health by changing cell signals in mice.
research Transient Calcium Entry by Plasmalogen-Mediated Activation of Receptor Potential Cation Channel Promotes AMPK Activity
Plasmalogens activate a channel in cells that may stimulate hair growth.
research SOX2 in the Skin: Roles in Biology and Pathology
SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
research Lymphatic Vasculature and Hair Follicle Regeneration
Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
research Promotion of Mouse Ameloblast Proliferation by Lgr5 Mediated Integrin Signaling
CD61 is important for mouse tooth cell growth and works through Lgr5.
research Deciphering the Mesodermal Potency of Porcine Skin-Derived Progenitors by Microarray Analysis
Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
research Biological Significance of FoxN1 Gain-of-Function Mutations During T and B Lymphopoiesis in Juvenile Mice
FoxN1 overexpression in young mice harms immune cell and skin development.
research Investigation of the Molecular Identity of the Junctional Zone in Human Skin
GATA6 is important for maintaining and differentiating cells in a key area of human skin.
research Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-Epithelialization
Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
research Organ Regeneration Based on Developmental Biology: Past and Future
Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.
research Developmental Plasticity of Patterned and Regenerating Oral Organs
Fish teeth and taste bud densities are linked and can change between types due to shared genetic and molecular factors.