31 citations,
January 2014 in “International Journal of Trichology” The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
4 citations,
January 2018 in “Advances in Experimental Medicine and Biology” The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.
January 2000 in “BioScience” The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.
89 citations,
September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
February 2024 in “Frontiers in physiology” Lymphatic vessels are important for skin repair and could affect skin disease treatments.
47 citations,
October 2014 in “Expert Opinion on Emerging Drugs” New alopecia treatments aim for better results and fewer side effects.
43 citations,
March 2009 in “Journal of Cellular and Molecular Medicine” TGF-β2 plays a key role in human hair growth and development.
41 citations,
January 2020 in “BioMed Research International” Micrografts improve hair density and thickness without side effects.
26 citations,
May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
15 citations,
August 2020 in “American Journal of Pathology” Insulin helps heal corneal wounds and nerves in diabetic mice by activating the Wnt signaling pathway.
14 citations,
July 2015 in “Journal of Cosmetic Dermatology” Sebaceous glands in male pattern hair loss patients have more lobules and might cause early hair growth phase shifts.
25 citations,
May 2016 in “Progress in Biophysics & Molecular Biology” R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
19 citations,
August 2019 in “Expert Opinion on Therapeutic Targets” New treatments for hair loss may target specific pathways and generate new hair follicles.
16 citations,
March 2018 in “Seminars in Oncology” The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.
13 citations,
April 2020 in “Experimental Cell Research” PCAT1 helps hair growth by controlling miR-329/Wnt10b.
3 citations,
January 2019 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu” Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.
6 citations,
November 2021 in “Frontiers in immunology” STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.
1 citations,
January 2011 in “Springer eBooks” Histone demethylases play a key role in the development of many diseases and may be targets for treatment.
31 citations,
May 2019 in “Nature communications” Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
7 citations,
March 2017 in “Journal of dermatology” The conclusion is that accurately identifying folliculosebaceous tumors requires understanding their clinical signs and microscopic features.
43 citations,
February 2019 in “International immunology” Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
147 citations,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
78 citations,
October 2012 in “Biomaterials” Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.
5 citations,
January 2009 in “Dermato-endocrinology” ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
58 citations,
August 2015 in “The Indonesian Biomedical Journal” Different types of stem cells help maintain and heal skin.
105 citations,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
44 citations,
July 2016 in “Stem Cells Translational Medicine” Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
18 citations,
February 2017 in “Molecular Medicine Reports” Activating Notch signaling can kill basal cell carcinoma cells.
4 citations,
June 2022 in “BioMed Research International” Using mesenchymal stem cells or their exosomes is safe for COVID-19 patients and helps improve lung healing and oxygen levels.