research The Pioneer Factor SOX9 Competes for Epigenetic Factors to Switch Stem Cell Fates
SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.
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research Runx Family Genes in Tissue Stem Cell Dynamics
Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
research Lactate Dehydrogenase Activity Drives Hair Follicle Stem Cell Activation
Lactate production is important for activating hair growth stem cells.
research What Does the Concept of the Stem Cell Niche Really Mean Today?
Stem cell niches support, regulate, and coordinate stem cell functions.
research Stem Cell and Extracellular Matrix-Related Molecules Increase Following Melatonin Treatment in the Skin of Postmenopausal Rats
Melatonin treatment helps improve skin health in postmenopausal rats.
research Characterization of Cell Cycle Arrest and Terminal Differentiation in a Maximally Proliferative Human Epithelial Tissue: Lessons from the Human Hair Follicle Matrix
CIP/KIP proteins help stop cell division and support hair growth.
research Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling
The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
research The Force Is Strong with This One: Metabolism Overpowers Stem Cell Fate
Metabolism plays a key role in determining stem cell fate.
research Ferreting Out Stem Cells From Their Niches
New methods have greatly improved our understanding of stem cell behavior and roles in the body.
research Wounding Induces Dedifferentiation of Epidermal Gata6+ Cells and Acquisition of Stem Cell Properties
Wounded skin cells can revert to stem cells and help heal.
research Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation
Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
research Induced Pluripotent Stem Cell Approach to Hair Follicle Regeneration
iPSCs could help develop treatments for hair loss.
research Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells
Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
research Transcriptional Control of Epidermal Stem Cells
Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
research Identification of the Cell Lineage at the Origin of Basal Cell Carcinoma
Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
research Mouse Hair Cycle Expression Dynamics Modeled as Coupled Mesenchymal and Epithelial Oscillators
The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
research Functional Hair Follicle Regeneration by the Rearrangement of Stem Cells
Stem cells rearrangement regenerates functional hair follicles, potentially treating hair loss.
research Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research A Role for the TGF-β/BMP Co-Receptor Endoglin in the Molecular Oscillator That Regulates the Hair Follicle Cycle
Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.
research CCN2 Modulates Hair Follicle Cycling in Mice
The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
research Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling
Fat-related cells are important for initiating hair growth.
research Hardwiring Stem Cell Communication Through Tissue Structure
The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate
The extracellular matrix is crucial for controlling skin stem cell behavior and health.
research Regulation of Melanocyte Stem Cell Behavior by the Niche Microenvironment
The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
research Tp63-Expressing Adult Epithelial Stem Cells Cross Lineage Boundaries Revealing Latent Hairy Skin Competence
Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
research Stretching the Limits: From Homeostasis to Stem Cell Plasticity in Wound Healing and Cancer
Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
research Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin
The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
research Recent Advances on Skin-Resident Stem/Progenitor Cell Functions in Skin Regeneration, Aging, and Cancers and Novel Anti-Aging and Cancer Therapies
New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
research Smad1 and Smad5 but Not Smad8 Establish Stem Cell Quiescence Critical for Transforming Premature Hair Follicles During Morphogenesis to the Postnatal State
Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.