August 2023 in “International Journal of Molecular Sciences” Human skin xenografting could improve our understanding of skin development, renewal, and healing.
July 2023 in “Stem Cells Translational Medicine” Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.
May 2023 in “Frontiers in Immunology” Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.
January 2023 in “Biomaterials Science” Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
April 2021 in “IntechOpen eBooks” Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.
November 2020 in “IntechOpen eBooks” Not getting enough minerals can lead to health problems and shorter lifespans.
October 2023 in “Biomaterials” Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
November 2022 in “Journal of Nanobiotechnology” The developed system could effectively treat hair loss and promote hair growth.
January 2022 in “Stem cell biology and regenerative medicine” The document concludes that hair follicle regeneration involves various factors like stem cells, noncoding dsRNA, lymphatic vessels, growth factors, minoxidil, exosomes, and induced pluripotent stem cells.
106 citations,
October 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
401 citations,
January 2013 in “Postepy Dermatologii I Alergologii” The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
62 citations,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
61 citations,
June 2018 in “Proceedings of the National Academy of Sciences of the United States of America” Light can turn on hair growth cells through a nerve path starting in the eyes.
5 citations,
September 2011 in “Cell stem cell” Epigenetic changes are crucial for hair follicle stem cells to function properly.
1 citations,
September 2017 in “Frontiers in Laboratory Medicine” Gut flora changes could potentially indicate depression, but more research is needed.
1 citations,
November 2015 Dental pulp stem cells might not reliably become neurons.
January 2024 in “Burns and trauma” The skin microbiome helps heal wounds and can be targeted to improve healing.
June 2018 in “Advances in Cosmetic Surgery” Hair loss caused by genetics and hormones; more research needed for treatments.
February 2023 in “Pharmaceutics” 113 citations,
June 2019 in “F1000Research” Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
9 citations,
September 2009 in “PubMed” Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.
July 2024 in “International Journal of Molecular Sciences” RF-based therapies might help treat hair loss.
8 citations,
October 2016 in “Journal of Investigative Dermatology” MR antagonists may improve skin health and wound healing, especially in aging.
September 2017 in “Journal of Investigative Dermatology” BMPs are crucial for hair growth and their decrease by androgens leads to hair loss.
39 citations,
August 2008 in “Growth hormone & IGF research” Raspberry ketone may help grow hair and improve skin elasticity.
1 citations,
January 2019 in “Elsevier eBooks” Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
September 2017 in “Journal of Investigative Dermatology” Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.
September 2016 in “Journal of dermatological science” Adult skin cells can be used to create new hair in a lab.
77 citations,
July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.