research The Effects of Oral 5-Alpha Reductase Inhibitors on Penile Intracavernosal Pressures and Penile Morphology in a Rat Model
Oral finasteride and dutasteride may negatively affect erectile function in rats.
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research Antioxidant Enzyme Expression of mRNA and Protein in the Epididymis of Finasteride-Treated Male Rat Offspring During Postnatal Development
Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.
research MOF-Mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions by Controlling Gene Promoters
MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.
research Mediator 1 Ablation Induces Enamel-to-Hair Lineage Conversion in Mice Through Enhancer Dynamics
Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
research Case of Follicular Mucinosis: Nestin-Expression in Mucin-Producing Cells
A 29-year-old man had a jaw plaque diagnosed as follicular mucinosis, linked to nestin-positive hair follicle stem cells.
research Procyanidin B-2 and the Hair-Growing Activity of Proanthocyanidins
Procyanidin B-2 from apple juice significantly increases hair growth and may be more effective than minoxidil without side effects.
research Immune Niches for Hair Follicle Development and Homeostasis
Immune cells are crucial for hair growth and preventing hair loss.
research Revealing Novel Insights on How Oral Supplementation With Collagen Peptides May Prevent Hair Loss: Lessons From the Human Hair Follicle Organ Culture
Collagen peptides from marine and bovine sources may help prevent hair loss by affecting hair follicle stem cells differently.
research Botulinum Toxin A for Hair Loss Treatment: A Systematic Review of Efficacy, Safety, and Future Directions
Botulinum Toxin A may help with hair growth and has some side effects; more research is needed.
research Prostatic Cystic Hyperplasia in a Young Dog: Case Report
A young dog with an enlarged prostate and cysts improved significantly after treatment and surgery.
research Low-Intensity Ultrasound Protects Human Scalp Hair Follicles From Taxane-Induced Toxicity
Low-intensity ultrasound may protect hair follicles from damage caused by a common chemotherapy drug.
research Environmental Pathobiology of Frontal Fibrosing Alopecia: A Link Between Linalool Sensitization and FFA Development
Being allergic to linalool, a common fragrance ingredient, might contribute to developing frontal fibrosing alopecia.
research Fibrosing Alopecia in a Pattern Distribution: A Case Report
A woman's progressive hair loss was correctly diagnosed as a rare condition called fibrosing alopecia in a pattern distribution after initially being mistaken for a more common type.
research Typical Morphological Characteristics of the Skin Structure of the Hair Part of the Normal Human Head and with Hair Loss
Androgenic alopecia causes hair follicle degradation and skin restructuring, but some hair elements remain.
research MOF-Mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions by Controlling Gene Promoters
MOF controls skin development by regulating genes for mitochondria and cilia.
research Mediator 1 Ablation Induces Enamel-to-Hair Lineage Conversion Through Enhancer Dynamics
Removing Mediator 1 causes teeth cells to turn into hair cells.
research Reorganizing Niche Architecture Still Preserves Organ Function in the Hair Follicle
Changing the structure of the hair follicle's environment can affect hair quality but doesn't stop hair growth.
research Chromatin Architectural Protein CTCF Regulates Terminal Keratinocyte Differentiation in the Developing Epidermis and Hair Follicles
CTCF protein is essential for skin and hair follicle development in mice.
research The Role of the Leaky Gut in the Development of Alopecia Areata
A compromised gut may trigger the autoimmune hair loss condition Alopecia Areata.
research Defining the Molecular Signature of the Hair Follicle Dermal Sheath and Its Functional Requirement for Hair Cycle Progression During Catagen
The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.
research BMP Signaling in the Hair Follicle Stem Cell Niche Regulates Hair Growth and Skin Pigmentation
BMP signaling controls hair growth and skin color.
research Over- And Ectopic-Expression Of FoxN1 At Early Life Adversely Influences Lymphopoiesis
Early over-expression of FoxN1 harms immune and skin development.
research Concepts and Challenges in Hair Follicle Cloning
Hair follicle cloning is possible but faces many challenges before it can replace traditional hair transplants.
research Editors' Picks
New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.
research FoxN1 in K14 Promoter-Driven Epithelium Is Required for Generation and Maintenance of 3D-Thymus Medulla and Preventing Nude Phenotype in the Skin
FoxN1 gene is crucial for proper thymus structure and normal skin appearance.
research The Ludwig Pattern of Androgenetic Alopecia Is Due to a Hierarchy of Androgen Sensitivity Within Follicular Units That Leads to Selective Miniaturization and a Reduction in the Number of Terminal Hairs Per Follicular Unit
Ludwig pattern hair loss in women results from varying sensitivity in hair follicles, causing fewer visible hairs.
research Procyanidin B-2 Extracted from Apples Promotes Hair Growth: A Laboratory Study
Apple extract called procyanidin B-2 was found to greatly increase hair growth.
research The Secretory Clear Cell of the Eccrine Sweat Gland as the Probable Source of Excess Sweat Production in Hyperhidrosis
Eccrine sweat gland's clear cells likely cause excessive sweating in hyperhidrosis.
research Hair Growth Control by Innate Immunocytes: Perifollicular Macrophages Revisited
Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
research Impact of Adipose-Derived Stem Cells on Engineering Hair Follicle Germ-Like Tissue Grafts for Hair Regenerative Medicine
Adding human fat-derived stem cells to hair follicle grafts greatly increases hair growth.