research Keratins: Dynamic, Flexible Structural Proteins of Epithelial Cells
Keratin proteins in epithelial cells are dynamic and crucial for cell processes and disease understanding.
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research Generation of Folliculogenic Human Epithelial Stem Cells from Induced Pluripotent Stem Cells
Scientists created stem cells that can grow hair and skin.
research Evolution of Trichocyte Keratins
Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.
research Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions
Spermidine may help reduce hair loss and deserves further testing as a treatment.
research Vibrissa Hair Bulge Houses Two Populations of Skin Epithelial Stem Cells Distinct by Their Keratin Profile
There are two types of stem cells in rodent hair follicles, each with different keratin proteins.
research Immunohistochemical Expression of Keratins in Normal Ovine Skin and in Chronic Dermatitis Due to Sarcoptes Scabiei
Sheep with chronic Sarcoptes scabiei dermatitis have altered keratin expression in their skin.
research Deletion of Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2 in FoxD1-Lineage Mesenchymal Cells Leads to Congenital Truncal Alopecia
Removing HIF-P4H-2 from certain skin cells in mice causes hair loss on the body but not the head.
research The Development of an In Vitro Human Hair Follicle Organoid With a Complexity Similar to That In Vivo
Scientists created a lab-grown hair follicle model that behaves like real hair and could improve hair loss treatment research.
research Advanced Inhibition of Undesired Human Hair Growth by PPARγ Modulation
GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.
research ERK1/2 Pathway Involvement in Enhancement of Fatty Acids from Phaeodactylum Tricornutum Extract on Hair Follicle Cell Proliferation
Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.
research The Early Region of Trichodysplasia Spinulosa Polyomavirus Drives Proliferation, Altered Differentiation, and Ectopic Expression of Hair Follicle Differentiation Markers in Interfollicular Tail Epidermis
The early genes of a specific virus can cause abnormal skin cell growth and hair follicle changes.
research WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation
A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
research Epidermal Structure Created by Canine Hair Follicle Keratinocytes Enriched with Bulge Cells in a Three-Dimensional Skin Equivalent Model In Vitro: Implications for Regenerative Therapy of Canine Epidermis
Keratinocytes from dog hair follicles can create a functional skin layer in a lab model, useful for dog skin therapy.
research Epithelial Skin Biology: Stem Cells and Epidermal Homeostasis
The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
research Convergent Evolution of Cysteine-Rich Keratins in Hard Skin Appendages of Terrestrial Vertebrates
Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.
research In Vitro Assembly Properties of Human Type I and II Hair Keratins
Different combinations of human hair keratins affect how hair fibers form.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
research Epithelial Stem Cells: Turning Over New Leaves
Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
research Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle
Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
research Epithelial Stem Cells And Implications For Wound Repair
Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
research A Human Folliculoid Microsphere Assay for Exploring Epithelial-Mesenchymal Interactions in the Human Hair Follicle
HFMs can help study hair growth and test potential hair growth drugs.
research Strategies to Enhance Epithelial-Mesenchymal Interactions for Human Hair Follicle Bioengineering
Improving the environment and cell interactions is key for creating human hair in the lab.
research Cultured Nail Keratinocytes Express Hard Keratins Characteristic of Nail and Hair In Vivo
Lab-grown nail cells show characteristics similar to natural nail and hair.
research The Epithelial Stem Cell Niche in Skin
Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
research Tp63-Expressing Adult Epithelial Stem Cells Cross Lineage Boundaries Revealing Latent Hairy Skin Competence
Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
research Lineage Potential, Plasticity, and Environmental Reprogramming of Epithelial Stem/Progenitor Cells
Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.
research Molecular Profiling of Frontal Fibrosing Alopecia Reveals TH1 and JAK-STAT Up-Regulation with No Suppression of Hair Keratins
Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.
research Scaffolds for Epithelial and Hair Follicle Regeneration
Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
research Stabilization of Epithelial Beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis
Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.
research Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling
The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.