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Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.

Quick, selective detection of tadalafil and finasteride in human plasma developed.

LEF1 is essential for the development of airway glands and is regulated by the Wnt/ß-catenin pathway.

New nano composite helps reduce scars and regrow hair during burn wound healing.

Sebaceous glands are involved in various skin disorders, some treatable with medications like finasteride and minoxidil.

Vitamin A may influence hair loss conditions like alopecia, but more research is needed to understand how.

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

Leonuri Herba alkaloids may help treat hormone-induced enlarged prostate in rats.

The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

New treatments targeting fibrosis could improve urinary symptoms in BPH.

Kolaviron and quercetin may help treat prostate issues.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.

Hair color is influenced by genetics and can indicate certain health conditions.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

Cholecystokinin may help reduce skin inflammation in psoriasis.

Benign skin tumors need accurate diagnosis to ensure proper treatment.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Androgens can both increase and decrease hair growth in different parts of the body.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.