32 citations,
July 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
11 citations,
January 2001 in “Cambridge University Press eBooks” Androgens can cause hair growth in some areas but hair loss on the scalp.
January 2017 in “Springer eBooks” Scientists made working hair follicles using stem cells, helping future hair loss treatments.
107 citations,
June 1997 in “PubMed” EGFR is essential for normal hair development and follicle differentiation.
70 citations,
January 2009 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Androgens slow hair growth by altering Wnt signaling in balding cells.
December 2023 in “Animals” The study mapped yak skin cells to understand hair growth better.
276 citations,
April 2003 in “Molecular endocrinology” Vitamin D is important for bones, hair, blood pressure, and breast development.
9 citations,
October 2008 in “Mutation research” N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.
46 citations,
January 1991 in “Journal of Investigative Dermatology” Minoxidil works in liver and outer hair root sheath for hair growth.
6 citations,
June 2022 in “Frontiers in Bioengineering and Biotechnology” The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.
1 citations,
April 2022 in “Regenerative Therapy” Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
2 citations,
January 2022 in “Journal of Investigative Dermatology” Hedgehog signaling in skin cells is crucial for hair growth and skin healing, but needs to be balanced to avoid harmful effects like scarring and cancer.
March 2024 in “International journal of molecular sciences” Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.
68 citations,
July 2011 in “Journal of Biochemistry/The journal of biochemistry” New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.
108 citations,
September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Lowering testosterone speeds up wound healing in male mice.
January 2017 in “Journal of Dermatology and Venereology” Naringenin and Hesperetin may help hair grow and protect hair cells from damage.
53 citations,
September 1999 in “The journal of cell biology/The Journal of cell biology” K16 can partially replace K14 but causes hair loss and skin issues.
4 citations,
October 2013 in “Springer eBooks” Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.
January 2025 in “Cell Communication and Signaling” CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
1 citations,
January 2017 in “Springer eBooks” The document explains how hair follicles develop, their structure, and how they grow.
56 citations,
September 2013 in “Experimental Dermatology” The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.
January 2025 in “Clinical and Translational Medicine” A specific RNA can help hair growth in baldness by boosting stem cell activity.
15 citations,
September 1999 in “British Journal of Dermatology” Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.
51 citations,
August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
27 citations,
June 2013 in “Genes & development” Cav1.2 affects hair growth and could be a target for hair loss treatments.
August 2022 in “Precision Clinical Medicine” JAM-A helps hair regrowth in alopecia areata by protecting VCAN in skin cells.
6 citations,
October 2016 in “Journal of Cellular Physiology” Human dermal fibroblasts help microvascular endothelial cells grow, but not vice versa.
July 2019 in “Dermatology practical & conceptual” The study found that alopecia areata is strongly linked to autoimmune diseases and may indicate a genetic predisposition to such conditions.
1 citations,
September 2015 in “Elsevier eBooks” SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
83 citations,
May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.