research Deletion of Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2 in FoxD1-Lineage Mesenchymal Cells Leads to Congenital Truncal Alopecia
Removing HIF-P4H-2 from certain skin cells in mice causes hair loss on the body but not the head.
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research Canonical Wnt-10b Signaling Exerts an Ability to Maintain Mouse Dermal Papilla Cells
Wnt-10b is important for keeping mouse skin cells healthy for hair growth.
research Hairless: A Nuclear Receptor Corepressor Essential for Skin Function
The Hairless gene is crucial for healthy skin and hair growth.
research Human Clinical Phenotype Associated With FOXN1 Mutations
FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.
research Botulinum Toxin A for Hair Loss Treatment: A Systematic Review of Efficacy, Safety, and Future Directions
Botulinum Toxin A may help with hair growth and has some side effects; more research is needed.
research Concepts and Challenges in Hair Follicle Cloning
Hair follicle cloning is possible but faces many challenges before it can replace traditional hair transplants.
research Mouse Notch: Expression in Hair Follicles Correlates with Cell Fate Determination
Mouse Notch is important for determining cell roles in hair follicles.
research Evolution of Trichocyte Keratins
Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.
research Combined Oral Contraceptives Promote Androgen Receptor And Estrogen Receptor Alpha Upregulation In The Female Prostate (Skene’s Paraurethral Glands) Of Adult Gerbils (Meriones Unguiculatus)
Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.
research Neutrophil Gelatinase-Associated Lipocalin Is a Marker for Dysregulated Keratinocyte Differentiation in Human Skin
NGAL indicates abnormal skin cell differentiation.
research Stem Cell Heterogeneity and Plasticity in Epithelia
Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
research 25 Years of Epidermal Stem Cell Research
Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
research Runx3 Is Involved in Hair Shape Determination
Runx3 helps determine hair shape.
research Advanced Therapies for Skin Injuries
New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
research 4th Intercontinental Meeting of Hair Research Societies 2004: The World of Hair
The meeting presented new findings on hair stem cells, pigmentation, genetics, and modern hair treatment techniques.
research Activation of Olfactory Receptor 2A4/7 by Cyclohexyl Salicylate Promotes Human Hair Follicle Growth
The fragrance cyclohexyl salicylate helps promote hair growth and increase hair stem cell numbers.
research Morphogenetic Events in Hair Follicle Heterotypic Spheroids
Researchers developed a method to create artificial hair follicles that may help with hair loss treatment and research.
research Hairy Math: Addition of Wnt-3a to Multiply Bulge Cells
Wnt-3a helps grow more skin stem cells, which could lead to new hair loss treatments.
research The Hair Cycle
The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
research Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth
Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.
research Regeneration of Dermis: Scarring and Cells Involved
Different fibroblasts play key roles in skin healing and scarring.
research The Hair Cycle
The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
research Learning From Nudity: Lessons From The Nude Phenotype
The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
research Resident Memory T Cells in Autoimmune Skin Diseases
Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.
research Evaluating Hair Growth Promoting Effects of Candidate Substances: A Review of Research Methods
The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
research Bioprinting of Hair Follicle Germs for Hair Regenerative Medicine
The study developed a new way to create hair-growing tissue that can help regenerate hair follicles and control hair growth direction.
research Anatomy and Physiology of Hair
Hair is important for protection, social interaction, and temperature control, and is made of a growth cycle-influenced follicle and a complex shaft.
research Prevention of Alopecia in Medical and Interventional Chemotherapy Patients
Cold caps and certain drugs may help prevent or reduce hair loss from chemotherapy, but more research is needed.
research STIM1 R304W in Mice Causes Subgingival Hair Growth and Increased Trabecular Bone Fraction
The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.
research Functional Ectodermal Organ Regeneration as the Next Generation of Organ Replacement Therapy
The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.