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This study identified epiprofin as a highly tissue-specific nuclear protein that promotes cell proliferation, mainly expressed in the developing teeth, hair follicles, and limbs of embryonic mice.

This study found that Pannexin 3 plays a crucial role in skin development by regulating the transcription factor Epiprofin, affecting keratinocyte differentiation and hair follicle regeneration in mice.

This study found that Epiprofin acts as a negative regulator of parathyroid hormone transcription, with potential implications for controlling PTH production in hyperparathyroidism.

This study indicates that the Sp6 gene is crucial for the development of skin, teeth, limbs, and lungs in mice, possibly through regulating apoptosis.

This study found that Sp6 overproduction in ameloblast-lineage cells increased cell proliferation and ameloblastin expression, suggesting that Sp6 promotes amelogenesis by inhibiting follistatin gene expression.

This study reports the preparation of a key intermediate for finasteride and epristeride with a 69% overall yield from pregnenolone acetate.

This study found that the JMJD3/NF-κB-Notch1 pathway plays a crucial role in regulating keratinocyte migration and skin wound healing, with Notch1 affecting key genes involved in cell migration.

This review discusses the progress in tooth regeneration research and highlights the potential of spatial-temporal release of developmental factors, but it reports no new clinical findings.

In this study, thymosin beta4 over-expression in transgenic mice was linked to accelerated hair growth and abnormal tooth development, suggesting roles in hair and tooth physiology.

This review discusses the regulation and dynamics of the Wnt/β-catenin signaling pathway in development, pluripotency, and cancer, highlighting potential mechanisms and future research directions, but reports no new results.

This study found that Wnt10a expression in odontoblasts increased with dental pulp regeneration and may be a potential non-cellular agent for inducing dental pulp regeneration with dentine-inducing capacity.

This study concluded that a synthesis process for finasteride from pregnenolone acetic ester is inexpensive, simple, and achieves a good yield of 36.5%.

This study developed a new method for synthesizing finasteride that eliminates the need for expensive and toxic chemicals, achieving high purity and a 24.2% yield.

This study found that a new hybrid compound designed from finasteride and epristeride was a potent inhibitor of 5α-reductase with a mechanism similar to finasteride.

In this study, finasteride was found to induce tissue-specific P-glycoprotein activity in the liver and kidney of rabbits after a 14-day treatment period.

Method quickly measures finasteride concentration in capsules.

This study identified CYP3A4 as a key isozyme involved in the oxidative metabolism of finasteride in human liver microsomes.

This study in humans and pigs found that finasteride metabolism is significantly influenced by CYP3A4, with induced metabolism decreasing and inhibited metabolism increasing plasma exposure of the drug.

This study reports an improved and more cost-effective 7-step synthesis method for finasteride with an overall yield of 20.01%.

This study concluded that Flaxin tablets and the reference formulation are bioequivalent in terms of absorption rate and extent when administered as a single 5 mg dose to healthy male volunteers.

This study found that Finasteride treatment significantly reduced dihydrotestosterone and epidermal growth factor levels in benign prostatic hyperplasia tissue, particularly in the periurethral zone, while Flutamide decreased epidermal growth factor but not dihydrotestosterone.

This study found that the metabolic profile of finasteride in pigs closely matches that of humans, supporting the use of pigs for studying human drug metabolism.

This research outlines a chemical synthesis process for Finasteride, detailing the conversion of pregnadienolone acetate through various chemical reactions and modifications.

The method produces finasteride with a 92% yield.

This study found that injectable finasteride microspheres provided a sustained drug release with a minimal initial burst in albino rabbits compared to oral suspension.

This study describes the synthesis of finasteride from 4-androstene-3,17-dione in a seven-step process with an overall yield of 18.6%.

Quickly get finasteride from tablets using easy methods.

A new compound may effectively inhibit the enzyme linked to BPH and hair loss.