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The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Wnt ligands are crucial for hair growth and repair.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Cathepsin L is essential for normal hair growth and development.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Applying a special compound can promote hair growth without harmful side effects.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Nerves and chemicals in the body can affect hair growth and loss.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Thymosin β4 promotes hair growth by activating stem cells in hair follicles.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

Trichoscopy helps diagnose and monitor alopecia areata by looking at a combination of specific hair and scalp features.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

New antifungal treatments for a children's scalp infection are effective and safe, but it's not decided if they will become the preferred option over the old treatment.

Children with loose anagen hair have easily pluckable hair due to root sheath problems, and it might improve without treatment.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.