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Hair follicles repair 3D injuries using a 2D healing process.

Brg1 is crucial for keeping hair follicle stem cells and repairing skin, working with the Sonic Hedgehog pathway to promote hair growth.

Cyclooxygenase-2 overexpression in mice skin causes hair loss like human androgenetic alopecia.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Lactate production is important for activating hair growth stem cells.

Oxidative stress contributes to hair graying and loss as we age.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Low-dose oral minoxidil and spironolactone combo effectively reduces hair loss and improves hair density in women.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

BAF200 is essential for proper heart and coronary artery formation.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

Researchers identified specific genes that are important for mouse skin cell development and healing.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

The HOXC13 gene affects different hair proteins in cashmere goats in varied ways and is controlled by a feedback loop and other factors.

Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.

Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

Different problems with hair stem cell renewal can lead to hair loss.

Rabbit skin analysis showed changes in hair growth and identified miRNAs that may regulate hair follicle development.

The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.