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DNA methylation changes in women with PCOS could be used as disease markers and suggest new treatment targets.

Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

HDAC inhibitors, like Vorinostat and Entinostat, can help regrow hair in alopecia areata.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

Gonadal hormones significantly affect the severity of alopecia areata in mice.

DNA methylation changes are linked to hair growth cycles in goats.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Genomic approach finds new possible treatments for hair loss.

Curcumin may help reverse aging by targeting specific genes.

Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

Elaine Fuchs' research shows how skin stem cells maintain health, aid in healing, and are involved in cancer.

Histone modification is key in treating chronic inflammatory skin diseases.

Machine learning can predict how well patients with alopecia areata will respond to certain treatments.

Hair pattern in androgenetic alopecia overlaps with scalp and bone demarcations, with distinct gene profiles affecting susceptibility.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Blocking cholesterol production may help control hair loss in Primary Cicatricial Alopecia by affecting key regulators.

Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Rabbit skin analysis showed changes in hair growth and identified miRNAs that may regulate hair follicle development.

Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.