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30 / 1000+ results![Tailored chromatin modulation to promote tissue regeneration](/images/research/c7160d76-9a79-42fb-8b02-da887cac5816/small/19309.jpg)
research Tailored chromatin modulation to promote tissue regeneration
Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
![708 Promotion of hair growth in alopecia areata by topical treatment of HDAC inhibitors](/images/research/8ed96e71-bbe6-4a2d-8115-a801aac79f1e/small/31502.jpg)
research 708 Promotion of hair growth in alopecia areata by topical treatment of HDAC inhibitors
HDAC inhibitors, like Vorinostat and Entinostat, can help regrow hair in alopecia areata.
![Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets.](/images/research/16c71416-3a31-4de5-b145-ed4488884f40/small/32789.jpg)
research Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets.
Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
research Epigenetics of Colorectal Cancer
Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
![Gelişmekte olan insan fetüslerinin ve yetişkinlerin derisinde EZH2 ekspresyonu: karşılaştırmalı bir çalışma](/images/research/f10a1710-59f7-4b53-aade-de95e2c13c3e/small/32862.jpg)
research Gelişmekte olan insan fetüslerinin ve yetişkinlerin derisinde EZH2 ekspresyonu: karşılaştırmalı bir çalışma
EZH2 levels decrease as fetuses develop and are higher in adult skin, which may affect skin growth and repair.
![Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells](/images/research/614ca7f6-2b51-4343-9400-ed88c3938812/small/20902.jpg)
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.
![The effect of DNMTs and MBPs on hypomethylation in systemic lupus erythematosus](/images/research/4230aba5-9cb2-4a59-9d2e-05dc18f3be2b/small/14924.jpg)
research The effect of DNMTs and MBPs on hypomethylation in systemic lupus erythematosus
Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.
![Nuclear Topology, Epigenetics, and Keratinocyte Differentiation](/images/research/c777f52d-1380-46e3-9722-3d1c35ae948d/small/26306.jpg)
research Nuclear Topology, Epigenetics, and Keratinocyte Differentiation
Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.
![Noval advance of histone modification in inflammatory skin diseases and related treatment methods](/images/research/745c5b30-df56-4b1c-a9a0-6039ca9cf0ff/small/36102.jpg)
research Noval advance of histone modification in inflammatory skin diseases and related treatment methods
Histone modification is key in treating chronic inflammatory skin diseases.
![The Role of Histone Demethylases in Disease](/images/research/da4990a1-53a3-484e-84de-0d8be6dd5494/small/19892.jpg)
research The Role of Histone Demethylases in Disease
Histone demethylases play a key role in the development of many diseases and may be targets for treatment.
![Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1](/images/research/a4555612-d049-480f-9bd0-1d4c61de7ec0/small/19815.jpg)
research Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1
Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
![NF-κB in biology and targeted therapy: new insights and translational implications](/images/research/3276b8f5-6ea1-4fa0-9027-d33cd6387493/small/33435.jpg)
research NF-κB in biology and targeted therapy: new insights and translational implications
NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
![Stress-related skin disorders](/images/research/2745a771-a8f5-4662-b9b7-b158541cd93d/small/18427.jpg)
research Stress-related skin disorders
Stress can worsen skin conditions by affecting hormone levels and immune response.
![Toll-Like Receptor Function in Acute Wounds](/images/research/42aa1539-fada-4b12-ba7e-18cc2746132d/small/19500.jpg)
research Toll-Like Receptor Function in Acute Wounds
Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.
![PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis](/images/research/f00d8ea0-2049-4770-b315-7a8eb82576d2/small/19336.jpg)
research PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis
PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
![Implication of Human Bacterial Gut Microbiota on Immune-Mediated and Autoimmune Dermatological Diseases and Their Comorbidities: A Narrative Review](/images/research/215ea76f-2e7d-4352-898a-eff2f8c01880/small/30016.jpg)
research Implication of Human Bacterial Gut Microbiota on Immune-Mediated and Autoimmune Dermatological Diseases and Their Comorbidities: A Narrative Review
An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.
![Stem Cells Therapies in Basic Science and Translational Medicine: Current Status and Treatment Monitoring Strategies](/images/research/bd0e9c9f-b4f3-485a-ae0d-807b9f2cbf15/small/19872.jpg)
research Stem Cells Therapies in Basic Science and Translational Medicine: Current Status and Treatment Monitoring Strategies
Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
![LncRNA-599547 contributes the inductive property of dermal papilla cells in cashmere goat through miR-15b-5p/Wnt10b axis](/images/research/ad3903af-336f-4f3e-8fdc-c4dc625751c2/small/35196.jpg)
research LncRNA-599547 contributes the inductive property of dermal papilla cells in cashmere goat through miR-15b-5p/Wnt10b axis
A specific RNA in cashmere goats helps improve hair growth by interacting with certain molecules.
![Progranulin, a secreted tumorigenesis and dementia-related factor, regulates mouse hair growth](/images/research/bc9d10cf-f26e-4235-b464-3f305dde4d63/small/15004.jpg)
research Progranulin, a secreted tumorigenesis and dementia-related factor, regulates mouse hair growth
Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.
![In Vivo Monitoring of Survival and Proliferation of Hair Stem Cells in a Hair Follicle Generation Animal Model](/images/research/45db17f1-f284-4d2e-97ff-7cff40c81648/small/19772.jpg)
research In Vivo Monitoring of Survival and Proliferation of Hair Stem Cells in a Hair Follicle Generation Animal Model
The technique allowed noninvasive tracking of hair stem cell survival and growth, showing potential for hair loss research.
![Application of metal organic frameworks-based functional composite scaffolds in tissue engineering](/images/research/1be2788b-523e-4e05-9aa3-61fa31c6d27a/small/35707.jpg)
research Application of metal organic frameworks-based functional composite scaffolds in tissue engineering
Metal organic frameworks-based scaffolds show promise for tissue repair due to their unique properties.
![Androgen excess: a hallmark of polycystic ovary syndrome](/images/research/400998e5-592f-4fbe-9faa-7f5b6463911b/small/36570.jpg)
research Androgen excess: a hallmark of polycystic ovary syndrome
Excess androgens may cause PCOS, not just be a symptom.
![706 Predictive modeling of patient response to JAK/STAT inhibitors and dynamic patient-matching](/images/research/6ac19a06-5716-4501-9656-9fa63a77325b/small/31504.jpg)
research 706 Predictive modeling of patient response to JAK/STAT inhibitors and dynamic patient-matching
Machine learning can predict how well patients with alopecia areata will respond to certain treatments.
![Antioxidants and Mitochondrial Bioenergetics](/images/research/1da6b108-a53e-48e5-a756-e37d17eb3163/small/29858.jpg)
research Antioxidants and Mitochondrial Bioenergetics
Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.
research Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata
MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
research Sodium Valproate Improves Skin Flap Survival via Gamma-Aminobutyric Acid and Histone Deacetylase Inhibitory System
Sodium valproate helps skin healing by affecting GABA and histone deacetylase.
![Advanced polymer hydrogels that promote diabetic ulcer healing: mechanisms, classifications, and medical applications](/images/research/f8cc3635-ee5f-40fe-a8ac-cd129607fff4/small/19118.jpg)
research Advanced polymer hydrogels that promote diabetic ulcer healing: mechanisms, classifications, and medical applications
Special gels help heal diabetic foot sores and reduce the risk of amputation or death.
research Familial Frontal Fibrosing Alopecia
Familial frontal fibrosing alopecia is rare, mostly affects women, and often occurs between sisters or mother-daughter pairs.
![A Hairy Cituation – PADIs in Regeneration and Alopecia](/images/research/89cd9f85-f570-47a9-8423-0ff142768078/small/19218.jpg)
research A Hairy Cituation – PADIs in Regeneration and Alopecia
Enzymes called PADIs play a key role in hair growth and loss.