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Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

Cannabinoids may help treat various skin conditions.

Dermal adipose tissue in mice can change and revert to help with skin health.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

Ectodysplasin inhibits Wnt signaling to help form hair follicles.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Sostdc1 controls the size and number of hair and mammary gland structures.

Certain genes in Iranian sheep are linked to wool production and heat adaptation.

New therapies are being developed that target integrin pathways to treat various diseases.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Significant progress was made in understanding PXE, but effective treatments are still needed.

MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.

Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Metabolism plays a key role in determining stem cell fate.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

BMP signaling is essential for the development of touch domes.

Combined arsenic and low oxygen stress alters root growth to help plants absorb nutrients.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

Autofluorescence can sort plant cells without labeling.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

VDR regulation varies by tissue and is crucial for its biological functions.