18 citations
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February 2019 in “Scientific Reports” This study found that TSA restored the hair-inductive capacity of skin-derived precursors in mice by enhancing BMP gene expression and signaling through histone acetylation.
11 citations
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May 2023 in “Journal of Cancer Research and Clinical Oncology” This review discusses various applications of CRISPR-based tools in cancer research, emphasizing their potential for investigating microRNA functions and developing microRNA-based therapies, despite challenges like off-target effects and delivery issues in using CRISPR/Cas9.
8 citations
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May 2022 in “International journal of nanomedicine” This study developed a fully natural resveratrol nanoparticle system using lecithin, showing potent anti-cancer activity in vitro and increased tumoral uptake in vivo on breast cancer models.
6 citations
,
December 2021 in “Scientific Reports” This study found that inhibiting class I histone deacetylases in postnatal mouse dermal cells preserved their ability to induce hair follicles during culture by increasing specific gene expressions and activating the Wnt signaling pathway.
5 citations
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October 2018 in “Journal of Clinical Laboratory Analysis” This study found that improved testosterone measurement using LC-MS/MS in women with PCOS revealed a stronger correlation between hyperandrogenism and insulin resistance than previously detected.
2 citations
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January 2019 in “Medizinische Genetik” Among families with pediatric brain disease, this study identified over 200 novel genetic causes, revealing potential treatment points using drug repurposing or nutritional supplementation.
1 citations
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July 2023 in “Nature communications” This study found that deleting the Mof gene in mouse skin leads to severe defects in skin cell self-renewal, differentiation, and hair follicle growth, indicating that MOF is crucial for mitochondrial and ciliary gene expression and essential for skin development.
1 citations
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January 2016 in “Elsevier eBooks” This review examines the origins and mechanisms of tumor initiation in common skin cancers, but does not present new experimental findings; it emphasizes the need for further research on cancer stem cells.
1 citations
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January 2015 in “Advanced techniques in biology & medicine” This study found that among patients with Down syndrome, those with alopecia areata may have increased antiperoxidase antibodies, possibly linked to hypothyroidism.
February 2025 in “Brazilian Journal of Hair Health” This study found that multiparametric ultrasound effectively detects real-time scalp changes caused by vasoconstrictive cosmetic agents, demonstrating its potential as a non-invasive tool for evaluating trichological treatments.
June 2024 in “Research Square (Research Square)” This study found that among young women in West Bengal, India, co-occurring PCOS and related conditions like estrogen resistance and leptin receptor insufficiency are common, with notable genetic variations identified, including impairments in leptin signaling and insulin resistance.
April 2021 in “Journal of Investigative Dermatology” In this study, researchers observed that different ERK signal activation dynamics during hair follicle regeneration are linked to cell fate specification and are affected by distinct upstream signaling pathways.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that deleting all three Tet genes in mice led to shorter hair shafts and altered hair types, with associated changes in gene expression and DNA hydroxymethylation.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, mouse sebaceous glands were found to require nerves for growth during active hair cycles, suggesting a nerve-dependent sebaceous gland cycle coordinated with hair growth.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, the researchers observed that post-radiation hair follicle repair in 3D architecture occurs through independent, long-range cell movements along the basal surface, resembling 2D healing processes.
April 2013 in “Developmental Cell” This study found that the chromatin remodeler Brg1 plays a crucial role in hair follicle maintenance and epidermal repair by regulating the Shh signaling pathway and forming a positive feedback loop.
January 2008 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” Healthy aging can be promoted through physical activity, lifestyle changes, and certain treatments.
April 2021 in “Journal of Investigative Dermatology” This study developed a transgenic mouse model to explore androgenetic alopecia, finding that inducible COX2 expression led to sebaceous gland changes and hair miniaturization, with reversible effects upon reducing COX2.
58 citations
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November 2020 in “International Journal of Dermatology” COVID-19 may cause a temporary hair loss condition called telogen effluvium in some patients after recovery.
40 citations
,
January 2009 in “Skin Pharmacology and Physiology” This review discusses the potential use of cultured primary fetal cells from a single organ donation to produce therapeutic products, emphasizing the need for process consistency and safety verification, but reports no clinical results.
12 citations
,
May 2018 in “JAAD Case Reports” This case report describes a patient with psoriasis who experienced scalp hair darkening and increased growth during anti–IL-17 therapy.
3 citations
,
May 2002 in “Therapeutische Umschau” This article discusses the challenges in diagnosing and treating diffuse hair loss in women and emphasizes the importance of distinguishing between androgenetic alopecia, chronic telogen effluvium, and psychogenic pseudo effluvium, but reports no new clinical results.
2 citations
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November 2020 in “Der Hautarzt” This case report suggests an association between the use of Sitagliptin, a DPP-4 inhibitor, and the development of alopecia universalis in a diabetic patient.
2 citations
,
January 2012 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This review discusses therapeutic principles for managing hirsutism and androgenetic alopecia during the menopausal transition and peri-/postmenopause but reports no new clinical results.
1 citations
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May 2021 in “Journal Für Ästhetische Chirurgie” This source discusses the importance of preoperative preparation, including thorough informed consent and consultation, to prevent patient dissatisfaction and legal issues following autologous hair transplantation, as a defined specialist standard for the procedure does not currently exist.
This study found that among women with polycystic ovary syndrome, higher age, obesity, hirsutism, and having children were independently associated with increased metabolic risk.
January 2012 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This article discusses the role of androgens in skin conditions like acne and alopecia, emphasizing combined systemic and topical therapy approaches, but it reports no new clinical outcomes.
January 2011 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” This study found that postmenopausal women experience two distinct patterns of hair changes, with diffuse scalp hair loss linked to body hair loss and age, and frontal hair loss associated with increased facial hair and a younger age.
April 2005 in “Aktuelle Dermatologie” This article reviews advancements in hair cosmetics, including "cosmeceuticals" and new dermocosmetic strategies, and reports no new clinical results.
354 citations
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February 2011 in “Genes & Development” This study found that abolishing H3K27me3 in mouse skin by targeting Ezh2 and Ezh1 affects hair follicle development and epidermal behavior, revealing functional differences between these tissues.