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This study found that cultured foreskin is not suitable for studying H2A.J-related tissue changes during radiation-induced dermatitis due to existing high H2A.J expression and cytokine secretion even without irradiation.

This article reviews mammalian skin epidermis as a model for studying stem cell regulation, noting the utility of in vitro and ex vivo platforms, but it reports no new empirical findings.

This review highlights the regenerative abilities of *Xenopus laevis*, focusing on how tadpoles regrow complex tail structures and the cellular and molecular mechanisms behind this. It underscores *X. laevis* as a valuable model for understanding regeneration, with insights potentially advancing regenerative medicine.

This review discusses the complex and variable presentation of polycystic ovary syndrome, emphasizing the need for consistent diagnostic criteria and individualized treatment strategies but reports no new clinical results.

This review examines the potential role of gut microbiota and its metabolites in polycystic ovary syndrome (PCOS) and highlights the growing interest in this area; it reports no new clinical findings.

This review discusses the role of various genetic regulators in maintaining human mesenchymal stem cell stemness and highlights strategies for ex-vivo expansion, but reports no new clinical findings.

This study found that a combination of four transcription factors can transform mouse fibroblasts into cells resembling inner ear hair cells, potentially aiding research into hearing loss treatments.

This review highlights that genetically engineered mouse models are valuable for studying melanoma development and progression by mimicking human skin biology, revealing key signaling pathways and molecular mechanisms that contribute to melanoma heterogeneity and offering insights into potential therapeutic targets.

This review synthesizes the diverse roles of the transcription factor LHX2 in development, tissue maintenance, and injury repair across various organ systems, highlighting its potential therapeutic applications and significance in regenerative medicine, particularly in developmental disorders and tissue regeneration.

This study reviewed recent scientific evidence on the neuroendocrine and metabolic impacts of chronic use of 5-alpha reductase inhibitors, detailing its association with sexual dysfunction, mood disorders, insulin resistance, and other metabolic disorders, suggesting persistent biopsycho-social risks beyond transient side effects in users.

This review highlights that surface mechanical regulation can program macrophage behavior through specific mechanical cues on material surfaces, potentially advancing immunotherapies and regenerative medicine by enabling precise control over macrophage functions.

This review discusses the symptoms, causes, and treatment options for polycystic ovary syndrome and reports no new results; the authors highlight the role of lifestyle changes, medications, and fertility treatments.

This review highlights the critical role of microRNAs in regulating hair follicle biology, significantly impacting wool and cashmere development by modulating gene expression and signaling pathways in sheep and goats.

This study of monozygotic transgender male twins observed that consistent hormone therapy led to physical changes such as deepening voice and increased facial/body hair, with no reported mood-related adverse effects.

This review highlights the role of various signalling pathways, particularly the inhibitory BMP pathway, in regulating feather follicle development in poultry and discusses the application of biotechnology for enhancing poultry aesthetics, emphasizing the increasing importance of feather follicles in ice-fresh poultry sales in China.

In this study, researchers identified the miR-22-3p/CLIC4 signaling pathway as a key regulator in hair follicle miniaturization among androgenetic alopecia models, suggesting that targeting CLIC4-mediated sonic hedgehog pathway disruption may offer new therapeutic strategies for AGA treatment.

This study investigated premature greying and found lower levels of vitamin D and vitamin B12 in affected individuals compared to controls, associating micronutrient deficiencies with altered hair pigmentation, though no significant link between micronutrient deficiencies and inflammatory markers was observed.

In this study, researchers found that finasteride induces dysregulation of genes related to neuropsychiatric disorders, including the HOMER-3 gene associated with dementia, and propose exploring craniosacral osteopathic therapy's potential to modulate this gene's methylation profile and alleviate related symptoms.

This review examines the role and significance of next-generation sequencing technologies in forensic identification and other forensic applications, but reports no new findings.

In this review, researchers reported that PCOS remains a complex condition with ongoing diagnostic and therapeutic challenges, highlighting recent innovations in diagnosis and treatment that provide alternative options for cases unresponsive to standard care.

This study examines the significant role genetic factors play in the development of intervertebral disc herniation and protrusion and explores how advancements in molecular genetics and translational medicine might improve diagnosis, prevention, and treatment, ultimately aiming to enhance patient outcomes and quality of life.

In this mouse model study, researchers found that deleting the ASH2L gene in epidermal progenitor cells led to thinner epidermal layers, delayed hair follicle development, and reduced epidermal stem cell pools, with alterations in genes related to hair follicle development and the Notch signaling pathway.

This review discusses the therapeutic potential of stem cells from postnatal tissues for regenerative medicine, emphasizing their paracrine effects and the pluripotent potential of very small embryonic-like stem cells.

This review discusses genetic conditions linked to complete scalp alopecia in children, identifying six genetic causes, but reports no new clinical results.

This study observed that DNA methylation dynamics, including global hypermethylation and site-specific changes, influenced gene expression associated with immune activation and PI3K-Akt signaling during esophageal tissue regeneration with acellular grafts.

In this case report, a 17-year-old girl with secondary amenorrhea was evaluated for PCOS, highlighting the importance of assessing abnormal menstrual patterns for underlying conditions, and suggesting that hormonal birth control and lifestyle changes can help manage symptoms.

This study highlights a novel connection between the DNMT3B enzyme, metabolic flux, and the self-renewal and differentiation of human embryonic stem cells.

The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.

This study found that the RNA helicase DDX6 is essential for maintaining self-renewal in epidermal progenitor cells by promoting the translation of proliferation regulators and degrading differentiation-inducing mRNAs.

This study found that Sonic hedgehog signaling is crucial for Merkel cell development around hair follicles in mice, with Polycomb repressive complex 2 loss causing ectopic Merkel cells across all hair types.