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Lower SHBG levels may increase the risk of PCOS.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Prostaglandin D₂ might be targeted for new male pattern baldness treatments.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.

Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Topical finasteride helps regrow hair and reduce balding without side effects.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Finasteride can cause sexual problems and depression in young men.

The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.

COVID-19 may harm male fertility and damage the reproductive system.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.