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The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Notch-related genes play a key role in the development and cycling of hair follicles.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Keratinocytes control how melanocytes work.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

Dogs with generalized discoid lupus erythematosus have similar symptoms to humans and need continuous treatment.

Reflectance confocal microscopy is a useful, non-invasive tool for diagnosing some skin diseases, with potential for future improvements.

Scalp biopsies from dermatomyositis patients show chronic hair loss without scarring, with mucin and blood vessel changes being very common.

Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.

Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.

The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.

Stephen Rothman made important discoveries in dermatology, including the use of PABA in sunscreens, but never profited from his work.

Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Melanocytes are important for skin and hair color and protect the skin from UV damage.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

Metformin helps improve skin regeneration by increasing the growth of skin stem cells.

A cross-bred lamb with severe skin and movement issues had ichthyosis fetalis but normal vitamin A levels.

Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.

The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.

Decreased IGF-1R expression may contribute to sacrococcygeal pilonidal sinus development.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.

Skin stem cells can help improve skin repair and regeneration.

Near-infrared LED light improves skin rejuvenation and hair growth better than white LED light.

Meis1 is crucial for skin health and tumor development.