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Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.

Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

Vesiculobullous lesions should be considered part of canine cutaneous epitheliotropic T-cell lymphoma.

The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.

Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

The circadian clock influences the behavior and regeneration of stem cells in the body.

Using skin stem cells and certain molecules might lead to scar-free skin healing.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Epidermal stem cells show promise for treating orthopedic injuries and diseases.

MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.

Mice without the Sept4/ARTS gene heal wounds better due to more stem cells that don't die easily.

Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.