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    Did you mean Epidermal Atrophy?
    Glossary Epidermal Atrophy

    thinning of outer skin layer, making it fragile

    Epidermal atrophy refers to the thinning of the outermost layer of the skin, known as the epidermis. This condition can result in the skin becoming more fragile, less elastic, and more prone to injuries and infections. It is often associated with aging, prolonged use of topical corticosteroids, or certain medical conditions like chronic dermatitis.

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    Research 30 of 1000+

    1. Epithelial Cells in the Hair Follicle Bulge do not Contribute to Epidermal Regeneration after Glucocorticoid-Induced Cutaneous Atrophy 2007 · 23 citations
    2. Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia American Journal of Pathology · 2007 · 67 citations
    3. Alterations in epidermal stem cells within the pilosebaceous unit in atrophic acne scars Australasian journal of dermatology · 2024
    4. 575 Senescent atrophic epidermis retains Lrig1+ stem cells and loses Wnt signaling, a phenotype shared with CD44KO mice Journal of Investigative Dermatology · 2016 · 2 citations
    5. Faculty Opinions recommendation of Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2007
    6. Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling PLOS genetics · 2019 · 19 citations
    7. Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism PLoS Medicine · 2006 · 135 citations
    8. The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling Development · 2011 · 134 citations
    9. Ichthyosis, Follicular Atrophoderma, and Hypotrichosis Caused by Mutations in ST14 Is Associated with Impaired Profilaggrin Processing Journal of Investigative Dermatology · 2008 · 99 citations
    10. Lentiginosis within plaques of linear atrophoderma of Moulin: a twin-spotting phenomenon? British Journal of Dermatology · 2010 · 9 citations
    11. Stem Cells in the Hair Follicle and Interfollicular Epidermis of Mice following Topical Application of Fluocinolone Acetonide Journal of Investigative Dermatology · 2007 · 2 citations
    12. Sclero-Atrophic Reaction after Botulinum Toxin Injection Journal of Clinical Research in Dermatology · 2016
    13. Lichen planopilaris [cicatricial (scarring) alopecia] in a child International Journal of Dermatology · 2001 · 18 citations
    14. Linear morphea alopecia: New trichoscopy findings International Journal of Trichology · 2017 · 2 citations
    15. Changes in murine hair with dietary selenium excess or deficiency Experimental Dermatology · 2011 · 6 citations
    16. Dorsal Skin Reactions of Hairless Dogs to Topical Treatment with Corticosteroids Toxicologic pathology · 1999 · 36 citations
    17. Thyroid hormone action on skin. PubMed · 2011 · 24 citations
    18. Morphologic and immunologic characterization of a canine isthmus mural folliculitis resembling pseudopelade of humans Veterinary Dermatology · 2000 · 13 citations
    19. A novel actor in skin biology: the mineralocorticoid receptor Experimental dermatology · 2015 · 7 citations
    20. A clinical and histopathological study of cicatricial alopecia Our Dermatology Online · 2013 · 5 citations
    21. Lichen planopilaris International Journal of Dermatology · 2001 · 5 citations
    22. Dermoscopic features of discoid lupus erythematosus Dermatologica Sinica · 2012 · 2 citations
    23. The Skin at Different Ages 2014
    24. The Effect of Hairless Mutant Gene on The Thymus and Skin Under The C_(57)BL/6 Genetic Background Laboratory Animal Science and Administration · 2004
    25. Keratosis Follicularis The American Journal of the Medical Sciences · 1906
    26. Morphological changes in the skin in a rat model of stress-induced alopecia and their correction with nutrients Reports of Morphology · 2026
    27. Dose-Dependent Histopathological and Structural Impact of Chemical Hair-Straighteners on Scalp Epithelium and Hair-Fibres Using Albino Wistar Rats Sahel Journal of Life Sciences FUDMA · 2025
    28. Lupus cutáneo crónico Revista Dermatológica Centro Uraga · 2024
    29. Comparative histopathological analyses of non-scarring alopecia in systemic lupus erythematosus patients in Lagos Nigeria Nigerian Journal of Clinical Practice · 2023
    30. Correspondence Journal of the European Academy of Dermatology and Venereology · 1999