3 citations,
April 2022 in “Frontiers in Physiology” Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.
2 citations,
January 2017 in “AIMS cell and tissue engineering” Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.
March 2023 in “Scientific reports” Hair growth-related cells need the enzyme SCD1 to help maintain the area that supports hair growth.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
4 citations,
September 2021 in “Biomolecules” Using Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells together can improve healing, including wound healing, bone regeneration, and hair growth.
4 citations,
April 2013 in “Stem cell discovery” 1 citations,
August 2023 in “Nature communications” Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
205 citations,
April 2005 in “Journal of Investigative Dermatology” Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
28 citations,
March 2010 in “Histochemistry and cell biology” Skin cells can help create early hair-like structures in lab cultures.
3 citations,
February 2021 in “Experimental dermatology” Dermal papilla microtissues could be useful for initial hair growth drug testing.
19 citations,
January 2017 in “Stem Cells International” Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
214 citations,
April 2017 in “Cell” Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
165 citations,
June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
143 citations,
September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
132 citations,
August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
57 citations,
March 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
46 citations,
August 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Phosphatidic acid may help hair grow by affecting cell growth pathways.
23 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
12 citations,
September 2020 in “Stem cell research & therapy” Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
7 citations,
January 2013 in “BioMed research international” Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.
4 citations,
January 2015 in “Hair therapy & transplantation” Hair follicle stem cells could be used to treat the skin condition vitiligo.
2 citations,
March 2020 in “Cell” Elaine Fuchs' research shows how skin stem cells maintain health, aid in healing, and are involved in cancer.
March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Scientists can now create skin with hair by reprogramming cells in wounds.
417 citations,
September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
295 citations,
June 2009 in “Science” Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.
245 citations,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
62 citations,
February 2016 in “ACS Applied Materials & Interfaces” Technique creates 3D cell spheroids for hair-follicle regeneration.
31 citations,
August 2019 in “Regenerative Medicine” Human placenta hydrogel helps restore cells needed for hair growth.
17 citations,
February 2019 in “PubMed” Stem cells can help regenerate hair follicles.
12 citations,
November 2014 in “PLOS Computational Biology” The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.