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This study found that overexpressing Dsg3 in the suprabasal epidermis of transgenic mice resulted in flaking skin and abnormal hair growth, supporting Dsg3's role in regulating epidermal differentiation.

This study created transgenic mouse models with the LMNA gene mutation common in Hutchinson-Gilford progeria syndrome, revealing skin and teeth abnormalities related to transgene expression levels.

This study found that the zinc transporter ZIP10 is crucial for epidermal development, as it influences the activity of p63, promoting epidermal morphogenesis.

This study found that telomere shortening disrupts BMP/pSmad/P63 signaling, leading to skin atrophy via Follistatin up-regulation, and suggests potential therapeutic targets.

This study found that bulge keratinocytes in mice develop resistance to glucocorticoid treatment more slowly than interfollicular keratinocytes and do not significantly aid in repairing glucocorticoid-induced skin atrophy within five days.

In this study, application of salicylic acid solution on mouse skin showed histologic changes without causing wounds or inflammation, observed immediately and up to 48 hours after treatment.

In this study, hair bleaching with ammonium persulfate and hydrogen peroxide caused significant damage to hair structure and severe skin reactions in rats, highlighting the need for cautious bleaching procedures.

Some patients with Alopecia Areata experience itch due to immune cells and enzymes that cause itching.

This study reports that γ-ray exposure in rats led to dermal endothelial proliferation, new vessel formation around hair follicles, and increased inflammatory markers, suggesting possible early stimulatory effects on hair growth.

In this study, Pomeranians with non-illness, generalized alopecia did not exhibit adrenal or pituitary abnormalities, suggesting a breed-specific hormonal pattern as a potential cause rather than a functional adrenal anomaly.

This study evaluated the effects of topical glucocorticoids on human skin using non-invasive imaging methods and observed changes such as alterations in skin layer thickness, keratinocyte size, and collagen and elastin signal intensity.

This paper reviews the evidence connecting androgen deficiency to skin ageing in men, emphasizing that reduced testosterone exacerbates ageing signs like epidermal thinning and decreased elasticity and advocates for tailored skincare and aesthetics for this demographic.

This study reported that albino Wistar rats exposed to chemical hair straighteners showed significant hair fiber damage and scalp skin deterioration, which worsened with repeated and prolonged application, highlighting the cytotoxic potential of these products and potential systemic risks.

This review discusses the role of Foxc1 and type XVII collagen in hair follicle stem cell quiescence and aging, identifying mechanisms that relate to hair thinning and hair loss, and reports no new results.

This study suggests that intermediate-size hyaluronate fragments may enhance keratinocyte proliferation and improve skin thickness in atrophic conditions through a CD44-dependent mechanism.

This review explores how adipose-derived stem cells contribute to skin homeostasis and highlights recent advances in their clinical applications in dermatology, but it reports no new clinical results.

In this study, severe diffuse hair loss in patients with systemic lupus erythematosus was associated with distinct clinical, dermoscopic, and histopathological features, which improved alongside treatment of the underlying condition.

This article discusses tissue-expansion augmented scalp reduction as a surgical option for cicatricial alopecia patients who are otherwise not candidates for traditional hair replacement techniques, but it reports no new clinical results.

This study found that topical MR blockers alongside glucocorticoids may limit glucocorticoid-induced skin atrophy, suggesting MR's significant role in skin-related endocrinology.

The document concludes that hair biology is complex and there are still unanswered questions about hair loss and follicle changes.

This case study reports a 20-year-old laborer's progressive hair loss with scalp and body lesions, diagnosed as lichen planopilaris, leading to scarring alopecia resembling male-pattern baldness.

Mimicking growth factors in a topical solution can prolong hair growth phase and reduce hair loss without side effects.

This paper reviews the diverse skin, nail, and hair changes caused by medications, highlighting hyperpigmentation, alopecia, and nail structural alterations, but reports no new data.

Skin changes throughout life, from development before birth to aging effects like wrinkles, influenced by both genetics and environment.

This study characterized a novel form of mural folliculitis in dogs, resembling human pseudopelade, marked by persistent alopecia, lymphocyte infiltration, and severe follicular atrophy without effective treatment response.

This study found that cortisol and corticosterone led to thinning of the epidermis and hair follicle regression in fetal mouse skin, while testosterone promoted differentiation and sebaceous gland development.

In this study, testosterone-induced alopecia in male rats led to significant thinning and follicular degeneration, but treatment with adipose-derived stromal vascular fraction cells markedly improved these histological changes, suggesting a potential role in hair follicle regeneration.

This research found that Foxc1 promotes quiescence in hair follicle stem cells and identified COL17A1 depletion, due to DNA damage, as a cause of hair thinning and loss during aging.

This study found that epidermal growth factor treatment in male mice delayed normal skin development, inhibiting hair growth and follicle development by maintaining birth-level cell proliferation and differentiation for several days.

This study demonstrated that using PLGA nanoparticles to deliver chlorogenic acid significantly increased type 17 collagen production in human epidermal cells, indicating potential for improved skincare formulations.