research Dysregulation of Grainyhead-Like 3 Expression Causes Widespread Developmental Defects
Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.
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150-180 / 1000+ results research The Physicochemical, Biopharmaceutical, and In Vitro Efficacy Properties of Freeze-Dried Dexamethasone-Loaded Lipomers
Freeze-dried dexamethasone nanoparticles in a hydrogel are stable and effective for treating alopecia areata.
research Basal Cells in the Epidermis and Epidermal Differentiation
The exact identity of skin stem cells and how skin cells differentiate is not fully known.
research M2 Macrophages Promote Wound-Induced Hair Neogenesis Through the Production of Growth Factors
M2 macrophages help hair regrowth in wounds by making growth factors.
research Medical Management Options for Hair Loss
The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research Targeting the Stem Cell Niche: Role of Collagen XVII in Skin Aging and Wound Repair
Collagen XVII is important for skin aging and wound healing.
research Transcriptomic Analysis to Identify Protective Dermal Papilla Signature in Occipital Scalp
The research found genes that may protect certain scalp cells from hair loss.
research A Transient Dermal Niche and Dual Epidermal Programs Underlie Sweat Gland Development
Sweat gland development involves two unique skin cell programs and a temporary skin environment.
research Epidermal Stem Cell Diversity and Quiescence
Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
research Mice Lacking the Epidermal Retinol Dehydrogenases SDR16C5 and SDR16C6 Display Accelerated Hair Growth and Enlarged Meibomian Glands
Mice without certain skin enzymes have faster hair growth and bigger eye glands.
research Gene Therapy: Recent Advances and Applications in Dermatology
Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.
research Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing
Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
research Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles
Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
research Pleiotropic Role of Notch Signaling in Human Skin Diseases
Notch signaling disruptions can cause various skin diseases.
research ELL Facilitates RNA Polymerase II-Mediated Transcription of Human Epidermal Proliferation Genes
ELL is crucial for gene transcription related to skin cell growth.
research The De Novo DNA Methyltransferase DNMT3A Is Required for Epidermal Homeostasis
DNMT3A is crucial for healthy skin and hair growth.
research Artificial Infestation of Sarcoptes Scabiei in Rabbits Exhibits Progressive Pathological Changes, Apoptosis, and Keratinization in the Skin
Rabbits with Sarcoptes scabiei had thicker skin, cell death, and skin hardening.
research Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
research Growth Factors in Hair Organ Development and the Hair Growth Cycle
Growth factors are crucial for hair development and could help treat hair diseases.
research Epidermal Growth Factor Receptor Mutant T790M-L858R-V948R Inhibitor from Calophyllum Inophyllum L. Leaf as Potential Non-Small Cell Lung Cancer Drugs
A compound from Calophyllum inophyllum L. leaf may help treat non-small cell lung cancer.
research An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation
Estrogen affects hair growth and skin cell multiplication.
research Corticotropin-Releasing Hormone and the Skin
CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
research Age-Associated Inflammation Connects RAS-Induced Senescence to Stem Cell Dysfunction and Epidermal Malignancy
Older skin has higher cancer risk due to inflammation and stem cell issues.
research Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair
PDCD4 is important for controlling skin cell growth and healing.
research Therapeutic Effect of Rumex Japonicus Houtt. on DNCB-Induced Atopic Dermatitis-Like Skin Lesions in Balb/c Mice and Human Keratinocyte HaCaT Cells
Rumex japonicus Houtt. may be an effective treatment for atopic dermatitis by reducing inflammation.
research Skin Stem Cells: At The Frontier Between The Laboratory And Clinical Practice. Part 1: Epidermal Stem Cells
Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.
research Alopecia Areata Update
Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
research Progress on Mitochondria and Hair Follicle Development in Androgenetic Alopecia: Relationships and Therapeutic Perspectives
Maintaining healthy mitochondria may help treat hair loss.
research Down-Regulatory Role of Cholecystokinin on Psoriatic Epidermal Inflammation
Cholecystokinin may help reduce skin inflammation in psoriasis.