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Rubbing skin increases absorption of water-soluble drugs from lotions and creams, but not oil-soluble drugs.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

COVID-19 can cause significant hair loss.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

New technologies help us better understand how skin microbes affect skin diseases.

Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Superficial granulomatous pyoderma is a unique, mild form of skin disease that often heals without strong medication and responds well to milder treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Using dermoscopy to guide scalp biopsies is an effective way to diagnose cicatricial alopecia.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Hair thickness differences help diagnose hair loss severity.

Loose Anagen Syndrome causes easy-to-pull, thin hair, mainly in young girls, and improves with age.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.

DCPA is a chronic leg infection often related to Staphylococcus aureus, affecting mostly young men in India.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.

White and yellow dots indicate severe female hair loss in dark skin.

Improving how drugs are absorbed through the skin could better treat mange in wombats.

The document concludes that recent studies help tell apart desmoplastic trichoepitheliomas from other skin tumors, but more research is needed for clear differentiation.