research Signaling and Gene Expression for Water-Tolerant Legume Nodulation
The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.
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research A Fibrous Hybrid Patch Couples Cell-Derived Matrix and Poly(L-Lactide-Co-Caprolactone) for Endothelial Cells Delivery and Skin Wound Repair
The new patch made of cell matrix and a polymer improves wound healing and supports blood vessel growth.
research Keratin 71 Mutations: From Water Dogs to Woolly Hair
A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.
research The Role of Astrotactin2 in Regulating Mammalian Skin Polarity
Astrotactin2 affects hair follicle orientation and skin cell polarity.
research Therapies
The document concludes that low-dose acne treatment is most suitable for moderate acne, with high patient satisfaction and low relapse rates.
research Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene
A mouse gene mutation increases the risk of skin cancer.
research The Malignant Capacity of Skin Tumors Induced by Expression of a Mutant H-Ras Transgene Depends on the Cell Type Targeted
The risk of skin tumors becoming malignant depends on the specific skin cell type affected.
research Regulation of Keratin 9 in Nonpalmoplantar Keratinocytes by Palmoplantar Fibroblasts Through Epithelial-Mesenchymal Interactions
Nonpalmoplantar skin cells can be made to express keratin 9 by interacting with palmoplantar fibroblasts.
research A Novel Missense Mutation Affecting the Human Hairless Thyroid Receptor Interacting Domain 2 Causes Congenital Atrichia
A specific gene mutation causes congenital hair loss.
research Semidominant Inheritance in Epidermolytic Ichthyosis
Epidermolytic ichthyosis can be inherited in a semidominant way with mild symptoms in carriers.
research Pathogenesis and Management of TRPV3-Related Olmsted Syndrome
EGFR and mTOR inhibitors may help manage Olmsted syndrome symptoms.
research Whole Genome Sequencing Analysis of Alpaca Suggests TRPV3 as a Candidate Gene for the Suri Phenotype
The TRPV3 gene variant may cause the long-haired suri alpaca coat.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Genetics
Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.
research Cell Death in the Skin: Mechanisms and Implications
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Prolactin and the Skin: A Dermatological Perspective on an Ancient Pleiotropic Peptide Hormone
Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
research Hair Follicle Regeneration Using Grafted Rodent and Human Cells
Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research Regenerative Surgery in the Management of Leg Ulcers
Using a patient's own tissue for micro-grafts may effectively treat non-healing leg ulcers and relieve pain.
research Hair Follicle Miniaturization in a Woolly Hair Nevus
The boy with woolly hair nevus had thinner hair and abnormal hair follicles, which improved with treatment but worsened when treatment stopped.
research Integrin α3β1 in Hair Bulge Stem Cells Modulates CCN2 Expression and Promotes Skin Tumorigenesis
Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.
research A Guide to Cost-Effective Emollient Prescribing
Choose cost-effective emollients for dry skin conditions and prescribe appropriate amounts.
research Understanding the Role of Glycogen Metabolism in Human Hair Follicle Biology
Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.
research Flexible Fate Determination Ensures Robust Differentiation in the Skin Hair Follicle
Hair follicle stem cells can change their role to ensure proper hair development.
research 5-Bromo-2′-Deoxyuridine Induced Effluvium via p53-Mediated CD326-Positive Keratinocyte Apoptosis in C57BL/6 Mice
A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.
research Abstracts
Finasteride significantly increases scalp hair and prevents hair loss in young and middle-aged men.
research Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding
Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
research Cosmetics and Cosmeceutical Applications of Chitin, Chitosan, and Their Derivatives
Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.
research Development and Homeostasis of the Sebaceous Gland
The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
research The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle
Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.