85 citations,
December 2017 in “Developmental Biology” Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
60 citations,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
August 2019 in “Stem cells” New treatments for hair loss, fertility, and wound healing are being explored.
September 2014 in “Springer eBooks” Men and women experience skin aging differently due to changes in sex hormone levels with age.
20 citations,
January 2015 in “Polish Journal of Pathology” Reflectance confocal microscopy is a useful, non-invasive tool for diagnosing some skin diseases, with potential for future improvements.
12 citations,
September 2018 in “International Journal of Cosmetic Science” Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.
March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.
3 citations,
June 2023 in “Nano today” A special bioink with nanoparticles helps regrow hair by reducing inflammation and promoting hair growth signals.
December 2024 in “Animals” RORA may help regulate hair growth by affecting hair follicle stem cells.
1 citations,
July 2023 in “Journal of developmental biology” Bird foot scales develop differently and can repair but not fully regenerate due to the lack of specialized stem cell areas.
March 2024 in “Biomedicines” Mesenchymal stem cells show promise for effective skin repair and regeneration.
January 2019 in “Springer eBooks” Combination therapies might work better for some vitiligo patients, but results vary.
18 citations,
July 2022 in “Chemistry - an Asian journal” Scientists created a 3D printed skin that includes hair and layers similar to real skin using a special gel.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.
September 2023 in “Clinical anatomy” Forehead creases are formed by a tight connection between the skin and muscle through dense fibers, with changes in skin thickness and fewer skin appendages near the creases.
28 citations,
March 2010 in “Histochemistry and cell biology” Skin cells can help create early hair-like structures in lab cultures.
205 citations,
April 2005 in “Journal of Investigative Dermatology” Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
July 2022 in “International journal of surgery science” An elderly man had a rare, large skin cyst on his lower back, which was removed by surgery.
1 citations,
January 2019 in “Elsevier eBooks” New scaffold materials help heal severe skin wounds and improve skin regeneration.
3 citations,
May 2022 in “Oncogene” Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
1 citations,
December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Choosing the right method to separate skin layers is key for good skin cell research.
12 citations,
January 2021 in “Journal of Cutaneous and Aesthetic Surgery” Epidermal growth factor helps skin and hair regeneration but needs more research for better understanding.
2 citations,
July 2023 in “Cosmetics” Surfactants in shampoos and conditioners remove some but not all lipids from hair, and more research is needed to understand their full impact.
1 citations,
December 2015 in “The Egyptian Journal of Histology” Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.
74 citations,
June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
39 citations,
July 2021 in “Stem Cell Research & Therapy” Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.
January 2022 in “Nasza Dermatologia Online” Dermoscopy helps doctors recognize a type of benign skin tumor called pilomatricoma.
29 citations,
December 2019 in “Stem Cells Translational Medicine” Fully regenerating human hair follicles not yet achieved.
32 citations,
February 2019 in “eLife” BMP signaling is essential for the development of touch domes.
6 citations,
October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.