research Skin Biology
Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
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research Defining the Transcriptional Signature of Esophageal-to-Skin Lineage Conversion
Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
research Dynamic Signals for Hair Follicle Development and Regeneration
Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
research Beyond Goosebumps: Does the Arrector Pili Muscle Have a Role in Hair Loss?
The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
research Translational Frontiers: Insight From Lymphatics in Skin Regeneration
Lymphatic vessels are important for skin repair and could affect skin disease treatments.
research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions
New effective scar treatments are urgently needed due to the current options' limited success.
research Hair Organ Regeneration Via Bioengineered Hair Follicular Unit Transplantation
Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
research Spontaneous Tumor Regression in Keratoacanthomas Is Driven by Wnt/Retinoic Acid Signaling Cross-Talk
Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
research The Hair Follicle: Functions, Self-Renewal, and Alopecic Disorders
Dogs could be good models for studying human hair growth and hair loss.
research Developing Stratified Epithelia: Lessons from the Epidermis and Thymus
The skin and thymus develop similarly to protect and support immunity.
research The Role of the SLC39A Family of Zinc Transporters in Zinc Homeostasis in Skin
Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.
research In Vivo Monitoring of Hair Cycle Stages via Bioluminescence Imaging of Hair Follicle NG2 Cells
Bioluminescence imaging can track hair follicle cells and help study hair regrowth.
research Exosomes Derived from Fisetin-Treated Keratinocytes Mediate Hair Growth Promotion
Fisetin in fruits and vegetables helps hair growth in mice.
research MOF-Mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions by Controlling Gene Promoters
MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.
research In This Issue
Advancements in hair biology include new treatments and tools for hair growth and alopecia.
research Destruction of the Arrector Pili Muscle and Fat Infiltration in Androgenic Alopecia
Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.
research The Developing Immune Network in Human Prenatal Skin
Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.
research The Role of Versican in the Skin Extracellular Matrix and Its Interaction with Hyaluronic Acid
Hyaluronic acid and versican are important for skin healing and hair growth and might help in regenerative medicine.
research Skin Epidermis and Adnexa Regrowth Induced by Treatment With Artificial Dermal Template After Full-Thickness Skin Wound
Artificial dermal template treatment can stimulate complete skin and hair follicle regrowth.
research Exosomes: Breakthrough in Regenerative Medicine and a Way to Improve Quality of Life
Exosomes can help repair and heal tissues, improving health and vitality.
research The Hedgehog-GLI1 Pathway Is Important for Fibroproliferative Properties in Keloids and as a Candidate Therapeutic Target
Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.
research A New Path in Defining Light Parameters for Hair Growth: Discovery and Modulation of Photoreceptors in Human Hair Follicle
Blue light promotes hair growth by interacting with specific receptors in hair follicles.
research The Effect of Cilostazol, a Phosphodiesterase 3 (PDE3) Inhibitor, on Human Hair Growth with Dual Promoting Mechanisms
Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.
research An Appraisal of Laboratory Models of Androgenetic Alopecia: A Systematic Review
Better hair loss models needed for research.
research Hair Growth Stimulation by a Natural Remedy: Animal Studies
The plant extract remedy Satura® Rosta promotes hair growth and regrowth without negative effects.
research Perspectives in Dermatopathology: Telomeres and Telomerase in Aging and Cancer with Emphasis on Cutaneous Disease
Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.
research The Immune Functions of Keratinocytes in Skin Wound Healing
Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
research Blimp1+ Cells Generate Functional Mouse Sebaceous Gland Organoids In Vitro
Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
research Activation of Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth
Activating β-catenin in certain skin cells speeds up hair growth in mice.
research Expression Patterns of Gli-1, Pleckstrin Homology-Like Domain, Family A, Member 1, Transforming Growth Factor-β1/β2, and p63 in Sebaceous and Follicular Tumors
The research suggests that p63 and TGF-β1 may help determine tumor type and malignancy in hair follicle and sebaceous tumors.