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This study identified ectomesenchyme as a major source of epidermal stem cells in mouse skin, with ectomesenchymal keratinocytes occupying a significant portion of the epidermal stem cell-enriched population.

This study found that keratin 19 and nuclear galectin-1 binding can transiently express in interfollicular epidermal cells after adhesion, suggesting keratin 19 should not be solely used as a stem cell activity marker.

This animal study found that dermal papilla cells in hair follicles of chimeric mice can originate from various fibroblasts in the skin, challenging assumptions about their specific lineage.

This review discusses the developmental origins and diversity of dermal fibroblasts, focusing on their roles in epidermal and hair follicle growth, but reports no clinical results.

This study identified hair follicle stem cells as a source of squamous cell carcinoma in an inducible mouse model and proposes targeting these for future cancer therapies.

This study reviews the embryological origins, anatomical and histological structure, and key functions of the skin, emphasizing its protective, sensory, and regulatory roles, as well as the social and psychological impacts of post-lesion changes.

This study observed that thymol from Origanum marjoram essential oil significantly promoted hair regrowth and reduced inflammation in cyclophosphamide-induced alopecia in rabbits, with effects that were comparable to or exceeded those of betamethasone, highlighting its potential as a safer treatment alternative.

Understanding where cancer cells come from helps create better prevention and treatment methods.

This review discusses the origin, characteristics, and therapeutic potential of melanocyte stem cells in skin pigmentation disorders and reports no clinical results.

This review examines the origins and mechanisms of tumor initiation in common skin cancers, but does not present new experimental findings; it emphasizes the need for further research on cancer stem cells.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

This study found that seborrheic keratosis lesions contain high levels of hair sheath keratin, suggesting they may originate from the upper hair follicle.

This study developed an in vitro system to analyze human skin progenitor cells' ability to form hair peg-like structures, providing insights for engineering hair follicle organoids.

This review discusses melanocyte stem cells in hair follicles and their potential role in cell-based therapy for vitiligo, reporting no new experimental results.

This study observed that benign skin tumors were more common than malignant ones, with squamous cell carcinoma being the most frequent type among malignant tumors.

This review outlines the various fibroblast subsets in the skin dermis, their origins, and their influence on epidermal stem cell behavior, highlighting the role of the local dermal niche in stem cell plasticity.

In this study, the staining properties of two types of cysts, epidermal and pilar, were found to differ, supporting their origins from the epidermis and the trichilemmal hair follicle layer, respectively.

This study suggests that deregulation of sonic and desert hedgehog signaling in mouse skin can lead to altered epidermal stem cell activity and lesions similar to human basal cell carcinoma, indicating these cancers may originate outside the stem cell population.

This review highlights similarities in the development of thymus and skin epidermis, reporting no new results; the authors emphasize shared molecular mechanisms despite different embryonic origins.

In this study, researchers reported that specific immunoreactivity patterns observed in hair follicle stem cell markers suggest different origins for trichilemmoma, basal cell carcinoma, and squamous cell carcinoma in human skin tissues.

This review provides an overview of the molecular evolution of corneous beta-proteins in reptiles and birds, highlighting their distinct genetic origin and role in epidermal structures, but reports no new results.

This review discusses the embryonic origins and characteristics of various stem cell populations in the skin, but it provides no new experimental results.

In this study, basal cell carcinoma developed in Ptch-deficient mice only after chemical treatment, not skin wounding, suggesting a second unknown event is necessary for tumor formation.

This study suggests that supporting cells are the origin of regenerated hair cells in the avian basilar papilla, with epidermal growth factor as a potential trigger, and indicates a possibility of hair cell regeneration in mammalian vestibular epithelia.

This study found that nevoid basal cell carcinomas originate in the epidermis and upper hair follicles, resembling early nonnevoid basal cell carcinoma proliferations.

This study found that nevoid basal cell carcinomas originate in the epidermis and the upper part of the hair follicle, showing similarities to nonnevoid basal cell carcinomas.

This study found that mutant mice with the we/we wal/wal genotype exhibit significant defects in hair shaft structure and epidermis stratification, correlating with postnatal alopecia symptoms.

This classification proposal introduces a novel system for categorizing cutaneous adnexal cysts based on their origin in the folliculosebaceous unit and sweat glands, aiming to simplify and enhance understanding of these skin lesions.

This article proposes a new classification system for cutaneous adnexal cysts based on their origin in the folliculo-sebaceous unit and sweat glands, aiming to clarify their categorization and origins.

This review discusses the clonal or polyclonal nature of skin carcinomas and the stem cell origins of basal and squamous cell carcinomas but presents no new research findings.