102 citations,
December 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Restoring hair bulb immune privilege is crucial for managing alopecia areata.
68 citations,
June 2005 in “Expert Opinion on Therapeutic Targets” Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
59 citations,
April 2016 in “Cell Reports” EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
35 citations,
July 2007 in “Dermatologic clinics” Facial dark spots can be caused by the sun, genetics, makeup, or medicine, and are diagnosed by patient history and skin tests.
June 2020 in “Journal of Investigative Dermatology” Tiny particles from skin cells can help activate hair growth.
13 citations,
August 2019 in “Biological & Pharmaceutical Bulletin” Certain flavonoids help grow back colored hair after skin injury.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
249 citations,
April 2002 in “The FASEB journal” Human skin can make serotonin and melatonin.
150 citations,
April 1999 in “Dermatologic Clinics” Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.
114 citations,
April 2004 in “International Journal of Dermatology” Postinflammatory hyperpigmentation causes dark skin patches and needs personalized treatment.
84 citations,
April 2005 in “Dermatologic Clinics” Treatments for melanin disorders exist, but more effective options needed.
60 citations,
April 2006 in “International Journal of Dermatology” Surgical methods like suction blister grafting and split-thickness skin grafting are highly successful for vitiligo repigmentation, but choosing the right patients is crucial for success.
31 citations,
July 2017 in “Clinical Science” MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
30 citations,
April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
20 citations,
October 2018 in “American Journal of Clinical Dermatology” Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.
19 citations,
July 2007 in “Dermatologic clinics” Tailor treatments for vitiligo to patient needs for best results.
13 citations,
July 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
8 citations,
March 2017 in “Journal of Cosmetic and Laser Therapy” Punch grafting treats vitiligo faster but can cause a cobblestone look, while follicular hair transplantation is slower but looks better and has no side effects.
6 citations,
February 2014 in “Human & experimental toxicology” Testosterone injections can cause skin darkening and thickening.
3 citations,
June 2017 in “International Journal of Radiation Biology” Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.
March 2024 in “GSC Advanced Research and Reviews” Different light affects cell functions and can help treat skin conditions.
May 2021 in “GSC Advanced Research and Reviews” Hair color is influenced by genetics and can indicate certain health conditions.
October 2007 in “Journal of Investigative Dermatology” The document suggests a bacteria plays a significant role in acne rosacea and that white hair can regain color after transplant, meriting more research on reversing grey hair.
September 1999 in “The Journal of The British Menopause Society” The document concludes that skin aging in women can be caused by UV exposure and hormonal changes, and treatments like hormone replacement therapy and various skin therapies can help.
305 citations,
February 2007 in “Hormone and metabolic research” Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
252 citations,
January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
165 citations,
June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
159 citations,
July 2006 in “Endocrine Reviews” Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
47 citations,
January 2013 in “International Journal of Cosmetic Science” Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
39 citations,
January 2008 in “Journal of Endocrinology” SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.