research The Study of Growth Factors in Patients with Androgenic Alopecia
Growth factors greatly affect hair loss, with different levels seen in men, women, younger patients, and at the start of the condition.
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research The Origins of Skin Diversity: Lessons From Dermal Fibroblasts
New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.
research The Role of the VEGF, KGF, EGF, and TGF-β1 Growth Factors in the Pathogenesis of Telogen Effluvium in Women
Certain growth factors significantly affect hair loss in women with telogen effluvium.
research A Novel In Vivo Active Pemphigus Model Targeting Desmoglein 1 and Desmoglein 3: A Tool Representing All Pemphigus Variants
New mouse models of Pemphigus show severe symptoms and need better treatments.
research A Desmosomal Cadherin Controls Multipotent Hair Follicle Stem Cell Quiescence and Orchestrates Regeneration Through Adhesion Signaling
A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.
research Milestones in Photocarcinogenesis
UV radiation causes skin cancer, but sunscreens and certain drugs can help prevent it.
research Generalized Pruritus in Primary Sclerosing Cholangitis: Implications of Histamine Release by Lysophosphatidic Acid
A certain medication improved severe itching in a boy with liver and bowel disease by reducing histamine levels, suggesting a new treatment target.
research Preparation of Mohs Micrographic Surgery Frozen Sections: Three New Pearls Leading to a Simplified, More Effective Process
Three new techniques simplify and improve the preparation of tissue samples for skin cancer surgery.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Alopecia Areata in Childhood
Alopecia areata is relatively common in children, has a variable course, and shows different responses to treatment; thyroid testing is recommended for those affected.
research Beyond Expectations: The Role of Keratin Intermediate Filament Proteins in Epidermal Integrity
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research Skin: Basic Structure and Function
The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.
research Trichodynia Is a Distinguishing Symptom of Telogen Effluvium
Scalp pain is a common symptom in people with active hair loss from telogen effluvium.
research Chemotaxis in Psoriasis
Psoriasis patients have immune cells that respond more strongly to signals and stimuli due to an intrinsic cellular defect.
research Association of a Polymorphism in the Ornithine Decarboxylase Gene with Male Androgenetic Alopecia
research British Society for Dermatopathology 2011 Findings
Dermatologists give better information on pathology forms, hypersensitivity vasculitis is a common skin issue, misdiagnoses can occur, and various skin conditions are linked to loss of elastin or genetic factors.
research Adherence to Topical Hydrocortisone 17-Butyrate 0.1% in Different Vehicles in Adults with Atopic Dermatitis
Adults with atopic dermatitis showed similar adherence to different forms of hydrocortisone cream, but actual use varied despite self-reports of near-perfect usage.
research Editors' Picks
Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.
research Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails
Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.
research Trichomegaly of the Eyelashes Following Treatment with Cetuximab
Cetuximab can cause excessive eyelash growth.
research Keratosis Follicularis Spinulosa Decalvans in a Family
KFSD is a genetic disorder causing hair loss and skin issues, with no effective treatment.
research Cetuximab-Associated Elongation of the Eyelashes
Cetuximab can cause eyelash growth, which is rare but manageable.
research Effect of Wigs on Perceived Quality of Life in Androgenetic Alopecia Patients
Wigs greatly improve life quality for hair loss patients.
research Acne Tarda and Male-Pattern Baldness Unmasking Primary Ovarian Insufficiency: A Case and Review
A woman with acne and baldness was found to have a rare ovarian condition but successfully had a child through fertility treatment.
research Tendency to Underestimate the Severity of Androgenetic Alopecia
People often underestimate hair loss severity, with fewer seeking treatment, and it's more distressing for women.
research Down-Ranking the Threat of HSV-1: RANKL Upregulates MHC Class I Restricted Anti-Viral Immunity in Herpes Simplex Virus Infection
RANKL improves the immune response against herpes simplex virus by enhancing T cell activation and could help develop better treatments or vaccines.
research Molecular Correlation With Clinical Outcomes in an Open Label Clinical Trial of Oral Tofacitinib in Patients With Alopecia Areata
Tofacitinib helped most patients with alopecia areata regrow hair and changes in immune cells were linked to the treatment's effectiveness.
research Pyodermatitis Vegetans Associated with Multiple Myeloma
A skin condition called pyodermatitis vegetans was found in a patient with multiple myeloma for the first time.
research Expression of EZH2 in the Skin of Developing Human Fetuses and Adults: A Comparative Study
EZH2 levels decrease as fetuses develop and are higher in adult skin, which may affect skin growth and repair.
research A Rare Case of Cardiocutaneous Syndrome in a Young Child
A child with skin and tooth symptoms was found to have a genetic mutation causing cardiocutaneous syndrome, leading to heart problems.