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This study found that large excisional wounds in rats across seven strains do not regenerate new hair follicles, unlike in mice, possibly due to differences in epidermal competence and transcriptional profiles.

This study demonstrates that LES-hair can detect differential protein expression in specific regions of plucked hair follicles, suggesting its potential for research and clinical applications like monitoring treatment effects in alopecia and cancer therapies.

This protocol demonstrates that pharmacological inhibition of TGF-β signaling can enhance the proliferative capacity of mouse and human keratinocytes, facilitating their use in skin research and graft preparation.

In this study, the researchers observed that inducing and then withdrawing β-catenin expression in a bigenic mouse model caused reversible changes in skin morphology, indicating dependence on β-catenin signaling.

This report describes two cases of extensive alopecia areata successfully treated with a combination of intralesional corticosteroids and fractionated laser, suggesting the potential of laser treatment to promote hair regrowth.

This article discusses the lack of national credentialing for laser therapy practitioners and emphasizes the need for rigorous self-assessment and expertise, particularly when treating patients with darker skin, without presenting new research results.

Laser therapy helped new hair grow in scarred skin for three patients.

This study introduced a novel microscopy system using an Er3 + −doped femtosecond fiber laser, achieving detailed imaging of biological structures in plant and skin samples with improved spatial resolution for various applications, including in vivo imaging.

This review highlights the benefits of long-pulsed Nd:YAG lasers for hair removal in individuals with Fitzpatrick skin types IV-VI, offering deeper follicular targeting with reduced melanin interaction, and examines emerging technologies like radiofrequency and RF microneedling for safe treatment options in skin of color.

This study found that low-level laser therapy may enhance wound healing and reduce pain, swelling, and inflammation by increasing mitochondrial activity and oxidative stress, leading to greater protein synthesis and cell proliferation.

This study found that finasteride-loaded microemulsions using poloxamer 124 significantly enhanced skin penetration of the drug compared to a standard solution, primarily through targeting hair follicles via the transfollicular pathway, with intercluster, intercellular, and transcellular pathways contributing less.

This study suggests that selective photothermolysis of sebaceous glands using free electron laser pulses may offer a novel approach to treating acne by causing targeted thermal damage without affecting the epidermis.

This review discusses the mechanisms by which laser treatment affects hair structures and growth, highlighting its potential for permanent hair reduction and associated skin damage, but reports no new experimental results.

This study identified the distribution of keratin-associated proteins during cornification in the epidermis of reptiles, revealing unique structural characteristics in sauropsid keratin proteins compared to other vertebrates.

In this study, researchers found that coordinated intercellular Ca2+ signaling among basal stem cells in mice is crucial for cell cycle progression and tissue-wide communication during epidermal regeneration.

This study found that DermaCult™ Keratinocyte Expansion Medium allows for significantly extended growth of human epidermal keratinocytes while maintaining their differentiation potential.

This study found that bikunin is expressed in human keratinocytes and may play a role in regulating keratinocyte function during mitosis or inflammation.

This study found that noncultured epidermal cell transplantation is promising for treating stable vitiligo, achieving significant repigmentation and patient satisfaction based on objective and subjective evaluations.

In this study, researchers used atomic force microscopy to evaluate mechanical stiffness across different skin layers in six participants, finding the highest stiffness in the epidermis and lower stiffness as layers progress to subcutaneous tissue, enhancing understanding of skin's physical properties and aiding future research.

In this study, researchers found that Notch signaling is crucial for late-stage epidermal differentiation and postnatal hair cycle homeostasis by regulating hair follicle stem cell proliferation and differentiation.

Mouse tail skin has different keratinization near hair follicles and scales.

In this study, the combination of keratin-gelatin from poultry feathers promoted early acceptance and viability of full-thickness skin mesh grafts in experimental dogs compared to other treatments.

This study found that K15 is variably expressed in sheep and mouse hair follicles, with specific patterns suggesting a role in the early stages of keratinocyte differentiation.

This study found that dispersed hair follicle cells can be cultured successfully on collagen type IV, potentially offering an alternative to cultured epidermal keratinocytes for skin treatment.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The research observed that 40-nm self-assembled nanoparticles enhanced minoxidil penetration in hairy guinea pig skin compared to 130-nm nanoparticles, but this size effect was absent in hairless skin.

This study suggests that programmed cell death plays a crucial role in shaping the structure of the human epidermis and its appendages during development.

In this study, researchers found that in hairy guinea pig skin, minoxidil delivered via 40-nm nanoparticles had higher skin penetration than 130-nm nanoparticles, indicating nanoparticle size affects permeation.

This study found that keratin K14 expression occurs early in epidermal cell differentiation, while a hair-specific keratin is expressed later in hair matrix cells, suggesting developmental divergence between the two cell types.

This study demonstrated that murine monoclonal antibodies can reveal specific patterns of desmosomal cadherin expression, Dsc1 and Dsc3, in human tissues and cultured cells using immunofluorescence microscopy.