This study found that lysine carboxymethyl cysteinate helps protect the epidermis from UVB-induced damage by activating autophagy and restoring cornification processes in a skin model.
October 2022 in “Chinese Journal of Dermatology” This study observed that skin dryness does not seem to indicate impaired epidermal barrier function, as there was no negative correlation between stratum corneum water content and transepidermal water loss.
8 citations
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April 2022 in “Burns” In this study, researchers found that moisturizers like Alhydran and DermaCress provided superior hydration and occlusion compared to silicone gel, suggesting these moisturizers may be a patient-friendly and cost-effective alternative for scar management.
May 2026 in “Applied Sciences” In this review, the authors reported that sprout extracts, rich in bioactive compounds, show promising effects on skin health, such as enhancing collagen synthesis, improving hydration, and reducing inflammation, though most evidence comes from laboratory and animal studies.
January 2011 in “Zhongguo shiyong fuke yu chanke zazhi” This study concludes that hormone therapy can significantly improve skin hydration, elasticity, thickness, and reduce wrinkles by modulating various skin cells through estrogen receptors.
44 citations
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January 2004 in “American journal of clinical dermatology” This review covers various disorders of cornification and their treatments, offering clinical insights but reporting no new research findings.
August 2026 in “Scientific Reports” This study suggests that a Lentinula edodes extract can improve skin barrier function, hydration, and sebum regulation, possibly by modulating vitamin D pathways, in individuals with oily and acne-prone skin.
July 2026 in “Clinics in Dermatology” This review discusses the potential benefits of topical melatonin in aesthetic dermatology, including its antioxidant and protective properties for skin aging and photoaging, while also noting varying strengths of evidence across different skin conditions.
9 citations
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May 2020 in “Journal of Cosmetic Dermatology” This review discusses various follicular unit excision methods, punch designs, and motorized devices, highlighting their roles in reducing hair follicle transection rates and optimizing graft harvesting for individual patient characteristics.
4 citations
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November 2023 in “Journal of Cosmetic Dermatology” In this study, researchers found that negative pressure fractional microneedle radiofrequency significantly improved periorbital wrinkles, hydration, and dermal thickness in patients with periorbital aging, while also increasing orderly collagen and elastic fibers, with minimal adverse effects reported.
1 citations
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January 2012 in “Human health handbooks” This review discusses the essential role of linoleic acid in preventing deficiency symptoms and enhancing skin function, but notes that scientific knowledge on its potential therapeutic use for skin diseases remains limited.
20 citations
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June 2014 in “Pharmaceutical research” This study found that combining Aliaxin® Global Performance with Viscoderm® Skinkò E improved hydration and appearance of nasolabial folds more effectively than using Aliaxin® Global Performance alone.
January 2026 in “Molecular Nutrition & Food Research” This study found that Gynostemma pentaphyllum hydrodistillate and Damulin B exert significant anti-photoaging effects in UVB-irradiated models by reducing oxidative stress, improving ECM integrity, and enhancing skin hydration and elasticity.
52 citations
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December 2000 in “Archives of Dermatological Research” This study found that the stratum corneum of scalp skin in humans has distinct functional characteristics compared to the facial skin and volar forearm, including higher hydration levels and intermediate epidermal turnover rates.
12 citations
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January 2021 in “Journal of Cutaneous and Aesthetic Surgery” This systematic review describes current findings on the use of recombinant epidermal growth factor (rhEGF) for skin aging and wound healing, emphasizing its potential benefits but highlighting the need for more controlled studies to optimize dosing and treatment protocols.
1 citations
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May 2017 in “Asian journal of medical sciences” This study found that dietary supplementation with collagen, chondroitin sulfate, low-molecular weight hyaluronic acid, Pycnogenol®, and coenzyme Q10 significantly improved skin hydration, elasticity, nail hardness, and hair condition in patients with age-related dermatological changes after 12 weeks.
March 2025 in “Journal of Cosmetic Dermatology” This study explored the effects of TTFE on male androgenic alopecia, finding that topical application increased hair density, follicular diameter, and scalp hydration while reducing water loss and sebum production in a 12-week trial.
August 2019 in “Journal of Investigative Dermatology” This study found that tight junctions extend to the most superficial layer of the stratum granulosum in human skin, challenging previous claims of their limited presence in the epidermis.
3 citations
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April 2021 in “Elsevier eBooks” This article discusses the structure and functions of the integumentary system and wound healing processes, but it reports no new clinical findings.
August 2019 in “Journal of The American Academy of Dermatology” This study found that bleach baths using 0.005% hypochlorite directly affected serine protease expression in skin cells and reduced skin pH in patients with atopic dermatitis, suggesting potential therapeutic benefits.
December 2025 in “Materials Technology” In this laboratory study, researchers developed a genipin-stabilized asymmetric PLA/gelatin scaffold that mimics skin architecture, supports fibroblast proliferation, and closes scratches effectively, suggesting its potential for epidermal-dermal regeneration and applications in sensing or drug delivery.
September 2023 in “Journal of the American Academy of Dermatology” In this study, a cosmetic product with nano encapsulated cysteamine plus sunscreen significantly improved melasma symptoms and quality of life in adult women over 84 days, compared to sunscreen alone, without any medically relevant intolerance.
September 1998 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.
33 citations
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September 2019 in “Dermatologic Surgery” This study found that intradermal administration of adipose-derived stem cell–conditioned medium significantly increased hair density and dermal thickness, suggesting potential regenerative effects on both hair follicles and the interfollicular scalp in patients with alopecia.
November 2025 in “Cosmetics” This study evaluated a levan-based polysaccharide, POLEVAN®, in shampoo formulations and reported that it significantly increased hair glossiness by 24%, allowed a reduction of surfactant content by up to 50% without affecting foam, and maintained scalp moisturization similar to hyaluronic acid in a clinical setting.
140 citations
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January 2009 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This review discusses the application of liposomes in dermatology, highlighting their therapeutic value for drug stabilization, skin penetration enhancement, and treatment of hair follicle-associated disorders, but reports no new clinical results.
June 2017 in “Experimental dermatology” This article, a special issue on hair follicle biology and pathology, reports no new research findings.
February 2026 in “Clinical Cosmetic and Investigational Dermatology” This study found that mice exposed to low humidity showed altered epidermal gene expression, which was modulated by topical emollient application; this suggests emollients may help manage dry skin in low-humidity environments by affecting specific gene pathways.
83 citations
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January 2015 in “World Journal of Stem Cells” This review discusses current experimental approaches for regenerating human hair follicles using tissue engineering and isolated cells, but reports no successful strategies with adult cells yet found.
40 citations
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December 2012 in “PLoS ONE” This study found that selective deletion of Ctip2 in epidermal keratinocytes in adult mice leads to atopic dermatitis-like inflammation and suggests Ctip2 plays a crucial role in skin barrier maintenance and inflammatory regulation.