32 citations,
December 2018 in “Cytokine” Type I interferons play a key role in the development of various skin diseases.
32 citations,
January 2012 in “International Journal of Dermatology” Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.
16 citations,
October 2014 in “Oral surgery, oral medicine, oral pathology and oral radiology” Keratoacanthoma comes from hair follicle cells.
15 citations,
February 2019 in “Journal of clinical medicine” Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.
1 citations,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.
Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.
November 2019 in “Harper's Textbook of Pediatric Dermatology” The document is a detailed medical reference on skin and genetic disorders.
110 citations,
July 2017 in “Immunology” Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
106 citations,
September 2010 in “Stem cells” Skin-derived precursors in hair follicles come from different origins but function similarly.
97 citations,
September 2006 in “Pharmaceutical Research” No treatment fully prevents hair loss from chemotherapy yet.
76 citations,
November 2009 in “Medical Clinics of North America” Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
42 citations,
May 2003 in “Mini-reviews in Medicinal Chemistry” New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
34 citations,
January 2018 in “International Journal of Dermatology” Scalp cooling is the most effective FDA-approved method to prevent chemotherapy-induced hair loss, but more research is needed for other treatments.
28 citations,
January 2018 in “Biochemical Society Transactions” Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.
3 citations,
November 2018 in “Oncology issues” Cancer survivors often experience worse skin problems from treatment than expected, and working with dermatologists could help improve their condition.
1 citations,
December 2015 in “The Egyptian Journal of Histology” Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.
January 2018 in “Springer eBooks” Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.
215 citations,
March 2018 in “Archives of Toxicology” Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
83 citations,
June 2018 in “Frontiers in immunology” Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
75 citations,
August 2018 in “Biochemical pharmacology” Targeting the skin's endocannabinoid system could help treat skin disorders.
62 citations,
August 2018 in “Frontiers in Endocrinology” Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
38 citations,
September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
20 citations,
March 2005 in “Current Medicinal Chemistry” New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
19 citations,
June 2019 in “Clinical Drug Investigation” Platelet-rich plasma injections significantly improve hair density and thickness in both male and female pattern hair loss, especially in early stages.
16 citations,
March 2015 in “Clinical Cancer Research” The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.
12 citations,
March 2016 in “Life Sciences” The new chemotherapy combination of WP 631 and Epothilone B shows enhanced effectiveness against ovarian cancer but requires more research on its safety.
8 citations,
December 2018 in “Journal of Dermatological Treatment” The PRP-like cosmetic with biomimetic peptides is potentially effective and safe for treating alopecia areata.
2 citations,
January 2018 in “European journal of pediatric surgery reports” A baby girl's hair turned straight on one side due to a neck tumor and surgery, but it returned to curly as she recovered.
2 citations,
March 2005 in “Cancer biology & therapy” Bexxar treatment led to a high response rate in patients with advanced-stage, treatment-resistant follicular lymphoma.