research TGF-β Family Signaling in Stem Cells
TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
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research Abstracts from the Symposium on the Pathophysiology of Hair Growth Organized by the Institute of Dermatology at the Royal Society of Medicine, 29 October 1987
The symposium concluded that hair growth involves complex processes, including the hair follicle life cycle, the role of the dermal papilla, hair strength, pigmentation, and the impact of diseases and treatments like minoxidil on hair and skin.
research PRC1 Fine-Tunes Gene Repression and Activation to Safeguard Skin Epithelium Development and Stem Cell Specification
PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.
research Human TSC2-Null Fibroblast-Like Cells Induce Hair Follicle Neogenesis and Hamartoma Morphogenesis
Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
research Mitotic Activity in the Epidermis of the Rabbit Stimulated with Local Applications of Testosterone Propionate
Testosterone applied to rabbit skin increases skin cell growth and changes skin structure.
research Hair-Follicle Dermal Papilla and Sheath Fibroblasts Provide a Supportive Microenvironment for Human Skin Regeneration
Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.
research RANK as a Therapeutic Target in Cancer
RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
research Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding
After skin injury, adult mice can grow new hair follicles, and this process can be increased or stopped by manipulating Wnt signals.
research Thyroid Hormone Action on Skin
Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.
research Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing
Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
research Advances in Hair Diseases
The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.
research Prolactin and the Skin: A Dermatological Perspective on an Ancient Pleiotropic Peptide Hormone
Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
research Skin Organoids: A New Human Model for Developmental and Translational Research
Skin organoids are a promising new model for studying human skin development and testing treatments.
research Skin Melanocytes: Biology and Development
The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.
research Stem Cells and the Skin
Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
research Emerging Role of ILK and ELMO2 in the Integration of Adhesion and Migration Pathways
ILK and ELMO2 help cells move and stick together, important for wound healing and hair growth.
research Tp63-Expressing Adult Epithelial Stem Cells Cross Lineage Boundaries Revealing Latent Hairy Skin Competence
Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
research A Review of the Impact of Calorie Restriction on Stem Cell Potency
Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.
research Peer Review of Human Hair Shaft Proteomic Profiling: Individual Differences, Site Specificity, and Cuticle Analysis
The research found that people's hair proteins vary, especially by ethnicity and body part, which could help identify individuals in forensic science.
research Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion
The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
research A Neuroendocrinological Perspective on Human Hair Follicle Pigmentation
Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
research Control by a Hair’s Breadth: The Role of MicroRNAs in the Skin
MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
research Tuning Wnt Signals for More or Fewer Hairs
Changing Wnt signaling can lead to more or less hair growth and might help treat hair loss and skin conditions.
research Live Imaging of Stem Cells: Answering Old Questions and Raising New Ones
Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
research Suppression of Wnt/β-Catenin Signaling by EGF Receptor Is Required for Hair Follicle Development
Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
research Keratin Function and Regulation in Tissue Homeostasis and Pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Melasma in Men
Treating melasma in men is difficult, especially for the deeper skin layers, and may need more than just topical treatments.
research Sphingolipid Metabolism Orchestrates the Establishment of the Adult Hair Follicle Stem Cell Niche to Control Skin Homeostasis
A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
research Editors' Picks
ANp63 is crucial for skin integrity, new filaggrin gene mutations link to eczema, hair can regrow from non-stem cells, sunburns are increasing, and glucocorticoids help treat skin allergies by affecting immune cells.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.