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Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

New effective scar treatments are urgently needed due to the current options' limited success.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

CDP is crucial for lung and hair follicle cell development.

Blocking JAK-STAT signaling can lead to hair growth.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Cathepsin L is essential for normal hair growth and development.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

KGF and activin are crucial for skin healing and repair.