research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
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research Vitamin D Metabolism and Function in the Skin
Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
research Epidermal Wnt/β-Catenin Signaling Regulates Adipocyte Differentiation via Secretion of Adipogenic Factors
Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
research Development and Homeostasis of the Skin Epidermis
The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
research Adipocytes in Skin Health and Disease
Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
research New Investigational Drugs for Androgenetic Alopecia
Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.
research Epidermal Expression of the Truncated Prelamin A Causing Hutchinson-Gilford Progeria Syndrome: Effects on Keratinocytes, Hair, and Skin
Progerin affects cell shape but not hair or skin in mice.
research Hair Morphogenesis In Vitro: Formation of Hair Structures Suitable for Implantation
Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.
research Multipotent Nestin-Positive Stem Cells Reside in the Stroma of Human Eccrine and Apocrine Sweat Glands and Can Be Propagated Robustly In Vitro
Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
research Laminin 332 Is Indispensable for Homeostatic Epidermal Differentiation Programs
Laminin 332 is essential for normal skin cell behavior and structure.
research Generation of iPS-Derived Model Cells for Analyses of Hair Shaft Differentiation
Researchers created a mouse cell line to study hair growth and test hair growth drugs.
research Hair Regeneration Methods Using Cells Derived From Human Hair Follicles and Challenges to Overcome
Current hair regeneration methods show promise but face challenges in maintaining cell effectiveness and creating the right environment for hair growth.
research Dynamics and Epigenetics of the Epidermal Differentiation Complex
Epigenetic mechanisms control skin development by regulating gene expression.
research Regulation of Epidermal Proliferation and Hair Follicle Cycling by Synthetic Photostable Retinoid EC23
The synthetic retinoid EC23 thickens skin and promotes hair growth more effectively and with a lower dose than natural retinoids.
research Modulating the Stem Cell Niche for Tissue Regeneration
Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
research Review of Hair Follicle Dermal Cells
Dermal cells are key in controlling hair growth and could potentially be used in hair loss treatments, but more research is needed to improve hair regeneration methods.
research Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development
Mitochondrial reactive oxygen species are essential for skin and hair development.
research Lack of the Vitamin D Receptor Is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth
Vitamin D Receptor is crucial for normal skin and hair growth.
research Stem Cell Heterogeneity and Plasticity in Epithelia
Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
research Cell Death in the Skin: Mechanisms and Implications
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Epidermal Growth Factor as a Biological Switch in Hair Growth Cycle
EGF controls hair growth by regulating hair follicles' growth phases.
research Natural Killer Cells in Atopic and Autoimmune Skin Diseases
NK cells play a role in skin diseases like eczema and psoriasis.
research Epidermal Patterning and Induction of Different Hair Types During Mouse Embryonic Development
Different body areas in mice produce different hair types due to interactions between skin layers.
research Defining Hair Follicles in the Age of Stem Cell Bioengineering
The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.
research Principles and Mechanisms of Regeneration in the Mouse Model for Wound-Induced Hair Follicle Neogenesis
Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
research Therapeutic Potential of Stem Cells in Follicle Regeneration
Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
research TGFβ Signaling Regulates Lipogenesis in Human Sebaceous Gland Cells
TGFβ signaling prevents sebaceous gland cells from producing fats.
research Epidermal E-Cadherin Dependent β-Catenin Pathway Is Phytochemical Inducible and Accelerates Anagen Hair Cycling
A form of vitamin E promotes hair growth by activating a specific skin pathway.
research Transformation of Amnion Epithelium into Skin and Hair Follicles
Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.
research The Acyl-CoA Binding Protein Is Required For Normal Epidermal Barrier Function In Mice
ACBP is crucial for healthy skin in mice.