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Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.

Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Liposomes could improve how skin care products work but are costly and not very stable.

Lowering testosterone speeds up wound healing in male mice.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

Applying certain inhibitors to the skin can promote hair growth without harming cells.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

The document concludes that Cutaneous Lupus Erythematosus has different forms, is influenced by genetic and environmental factors, and can be treated with various medications, but more targeted therapies are needed.

Hair follicle stem cells are important for maintaining healthy skin and interact with many signals.

Hair follicle regeneration possible, more research needed.

Phloroglucinol may help improve hair loss by promoting hair growth and reducing oxidative stress.

Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.

Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.

The skin's microbiome helps hair regrow by boosting certain cell signals and metabolism.

Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

NIPP1 is important for healthy skin and could help treat skin inflammation.

The method effectively mimics shaving damage on skin for testing skincare products.

Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.

Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.

Non-liganded Vitamin D Receptor is crucial for healthy skin and hair.

Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.

Applying a special DNA plasmid to the skin can make it thicker and stronger.

Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.