research Role of Cholesterol Sulfate in Epidermal Structure and Function: Lessons from X-Linked Ichthyosis
Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
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research The Topography of Fibrous Scaffolds Modulates the Paracrine Function of Adipose-Derived Mesenchymal Stem Cells in the Regeneration of Skin Tissues
The shape of fibrous scaffolds can improve how stem cells help heal skin.
research RANK as a Therapeutic Target in Cancer
RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
research NIR-Responsive Multifunctional Artificial Skin for Regenerative Wound Healing
The artificial skin promotes better wound healing and skin regeneration.
research The Molecular Revolution in Cutaneous Biology: Noncoding RNAs as New Molecular Players in Dermatology and Cutaneous Biology
Non-coding RNAs are crucial for skin development and health.
research Histochemical and Immunohistochemical Markers for Human Eccrine and Apocrine Sweat Glands: An Aid for Histopathologic Differentiation of Sweat Gland Tumors
Markers help differentiate between apocrine and eccrine sweat glands to identify sweat gland tumors.
research Addition of Zinc and Selenium to Papaya Extract Enhances Its Efficiency of Wound Healing
Adding zinc to papaya extract speeds up wound healing.
research Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells
Adult mouse skin contains stem cells that can create new hair, skin, and oil glands.
research Deciphering the Role of the Hexosamine Pathway in Skin Homeostasis
The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.
research Endogenous Human Skin Equivalent Promotes In Vitro Morphogenesis of Follicle-Like Structures
Endo-HSE helps grow hair-like structures from human skin cells in the lab.
research Single-Cell Transcriptome Sequence Profiling on the Morphogenesis of Secondary Hair Follicles in Ordos Fine-Wool Sheep
The research identifies genes linked to wool quality in sheep and provides insights to improve wool production.
research Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes
Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
research Linear Morphea Alopecia: New Trichoscopy Findings
Trichoscopy can reveal specific hair and scalp changes in linear morphea.
research Small T Antigen From a Folliculotropic Polyomavirus Activates Canonical Wnt/β-Catenin Signaling In Vivo
A virus protein can activate a pathway that may lead to abnormal hair follicle development.
research Dermo-Epidermal Interactions in Reptilian Scales: Speculations on the Evolution of Scales, Feathers, and Hairs
Reptilian scales, feathers, and hairs evolved from changes in skin cell interactions.
research Fibroblast Growth Factor and Epidermal Growth Factor in Hair Development
FGF and EGF are crucial for hair follicle development and growth.
research The Autoimmune Regulator (AIRE), Defective in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients, Is Expressed in Human Epidermal and Follicular Keratinocytes and Associates With the Intermediate Filament Protein Cytokeratin 17
AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.
research Transdermal Delivery of Minoxidil with Block Copolymer Nanoparticles
Smaller nanoparticles improve minoxidil absorption through hair follicles.
research Hair Development and Langerhans Cell Migration During Human Embryogenesis
Langerhans cells and melanocytes migrate to the skin and hair follicles during early human development.
research Stem Cell and Extracellular Matrix-Related Molecules Increase Following Melatonin Treatment in the Skin of Postmenopausal Rats
Melatonin treatment helps improve skin health in postmenopausal rats.
research Applications of Platelet-Rich Plasma as Therapy in Dermatology
Platelet-rich plasma therapy helps heal skin ulcers and stimulates hair growth in dermatology.
research Epidermal Stem Cells and Skin Tissue Engineering in Hair Follicle Regeneration
Hair follicle regeneration needs special conditions and young cells.
research Transcriptional Control of Epidermal Stem Cells
Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
research The Effects of Sonic, Desert, and Indian Hedgehog Signaling in Skin
Shh and Dhh affect skin development and can cause tumors, while Ihh does not.
research The Effects of Multiple Power Densities of Carbon Dioxide Laser on Photothermal Damage in Rat Skin Tissue
Higher power CO2 laser causes more severe skin burns and damage.
research The Scientific Legacy of Stephen Rothman
Stephen Rothman made important discoveries in dermatology, including the use of PABA in sunscreens, but never profited from his work.
research Topically Applied N,N-Dimethylglycine Sodium Salt Enhances Human Skin Blood Flow by Inducing Endothelial Nitric Oxide Release
Applying DMG-Na to the skin increases blood flow and may help with skin conditions.
research Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling
Epidermal Growth Factor helps hair follicle cells grow and move by activating a specific cell signaling pathway.
research Cystatin M/E Is a High Affinity Inhibitor of Cathepsin V and Cathepsin L by a Reactive Site Distinct from the Legumain-binding Site
Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.
research Region-Specific Reversal of Epidermal Planar Polarity in the Rosette Fancy Mouse
Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.