research CD99 Is Strongly Expressed in Basal Cells of the Normal Adult Epidermis and Some Subpopulations of Appendages: Comparison with Developing Fetal Skin
CD99 is highly present in certain skin cells and could help treat skin conditions.
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research Development and Homeostasis of the Skin Epidermis
The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
research Understanding Melanocyte Stem Cells for Disease Modeling and Regenerative Medicine Applications
Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
research Cell Death by Cornification
Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
research CDermo-1 Misexpression Induces Dense Dermis, Feathers, and Scales
cDermo-1 causes dense skin, feathers, and scales in chickens.
research Molecular and Cellular Characterization of Avian Reticulate Scales and the Evolutionary Development of Skin Appendages in Foot Soles
Bird foot scales develop differently and can repair but not fully regenerate due to the lack of specialized stem cell areas.
research Tooth, Hair, and Claw: Comparing Epithelial Stem Cell Niches of Ectodermal Appendages
The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.
research Green-Prepared Magnesium Silicate Sprays Enhance the Repair of Burn Skin Wound and Appendages Regeneration in Rats and Minipigs
Magnesium Silicate Sprays help heal burn wounds and regrow skin features better than commercial products.
research Hedgehog Signaling in Papillary Fibroblasts Is Essential for Hair Follicle Regeneration During Wound Healing
Hedgehog signaling in certain cells is crucial for hair growth during wound healing.
research Engineering Pro-Regenerative Hydrogels for Scarless Wound Healing
Hydrogels could lead to better treatments for wound healing without scars.
research Hair Growth Promoting Effect of Zizyphus Jujuba Essential Oil
Zizyphus jujuba essential oil can promote hair growth.
research In Vivo Reprogramming of Wound-Resident Cells Generates Skin with Hair
Scientists can now create skin with hair by reprogramming cells in wounds.
research Oral Retinoids: Present Status
Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.
research Multipotent Nestin-Positive Stem Cells Reside in the Stroma of Human Eccrine and Apocrine Sweat Glands and Can Be Propagated Robustly In Vitro
Human sweat glands have a type of stem cell that can grow well and turn into different cell types.
research Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling
Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
research Generation of Skin Organoids: Potential Opportunities and Challenges
Skin organoids from stem cells could better mimic real skin but face challenges.
research The G-Protein Coupled Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
research Expression of Potential Dermal Progenitor Cell Markers in the Tumor and Stroma of Skin Adnexal Malignant and Benign Tumors
Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.
research Expression of EZH2 in the Skin of Developing Human Fetuses and Adults: A Comparative Study
EZH2 levels decrease as fetuses develop and are higher in adult skin, which may affect skin growth and repair.
research Genetic Basis of Skin Appendage Development
Hair, teeth, and mammary glands develop similarly at first but use different genes later.
research Cutaneous Tumors of Pilar Origin with Associated Syndromes
Some skin tumors from hair follicles and glands can be linked to genetic syndromes and may be benign or malignant.
research Dlx3 Is a Crucial Regulator of Hair Follicle Differentiation and Cycling
Dlx3 is essential for hair growth and regeneration.
research Skin Structure
Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
research Identification of Dkk4 as a Target of Eda-A1/Edar Pathway Reveals an Unexpected Role of Ectodysplasin as Inhibitor of Wnt Signaling in Ectodermal Placodes
Ectodysplasin inhibits Wnt signaling to help form hair follicles.
research Wnt4 Increases the Thickness of the Epidermis in Burn Wounds by Activating Canonical Wnt Signalling and Decreasing Cell Junctions Between Epidermal Cells
Wnt4 protein makes the outer skin layer thicker in burn wounds by turning on a specific healing pathway and loosening the connections between skin cells.
research Effect of Estrogens on Skin Aging and the Potential Role of SERMs
Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.
research Steatocystoma Multiplex
Steatocystoma multiplex causes recurring skin cysts and needs early recognition for better management.
research Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells
Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.
research Co-Editors' Messages
Inflammation linked to the immune response may play a role in causing various types of hair loss.
research Modeling of Solar UV-Induced Photodamage on the Hair Follicles in Human Skin Organoids
Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.