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This study found that deleting the miRNA processing enzymes Drosha and Dicer from mouse skin epithelial cells disrupted normal hair follicle development and maintenance, leading to follicular degradation and stem cell loss during the growth phase.

This study reveals that transglutaminase activity is widespread in integumentary structures of mammals and birds, suggesting it plays a significant role in the cornification of hard skin appendages like nails and feathers.

This study suggests that inorganic magnesium silicate sprays can improve burn wound repair and promote regeneration of skin appendages, showing superior results compared to commercial wound healing products in animal models.

In this study, Waved-5 mice with reduced EGFR signaling showed nearly normal skin and hair follicle function but experienced a transient reduction in subcutaneous fat.

This study found that overexpression of the mineralocorticoid receptor in a mouse model led to premature epidermal barrier development, keratinocyte apoptosis, and postnatal alopecia, indicating new roles for MR signaling in skin physiology.

This article reviews recent research on adult epidermal stem cells, discussing their properties and potential for reprogramming into patient-specific therapies, and emphasizes the need for further development while minimizing cancer risk.

This review discusses the regenerative processes of lizard tails, particularly focusing on the diversity in blastema development across different species, and reports no new findings.

In this study, forced expression of the transcription factor cDermo-1 in chicken dermis led to the formation of ectopic feather buds and enhanced feather growth, demonstrating its role in initiating skin appendage development.

Secreted inhibitors of Wnt and IGF signaling control hair and tooth development, creating species-specific patterns.

This paper reviews recent findings on epidermal development and stem cell regulation, listing key studies that contribute to understanding the molecular pathways involved in skin morphogenesis without reporting new experimental results.

This study investigated the molecular mechanisms of hair follicle morphogenesis in Ordos fine-wool sheep, identifying differential genes related to primary and secondary hair follicles, and providing important insights for improving wool quality and breeding strategies.

This article reviews the complex process of wound repair, emphasizing recent microarray studies and proteomic analyses, but reports no new clinical results.

This study found that Neuregulin3 can influence the development and differentiation of mammary glands and epidermal features in mice, potentially by inducing c-Myc and altering cell proliferation and adhesion.

This study found that C57BL/6 mice and Sprague–Dawley rats show distinct distributions of eccrine sweat glands and hair follicles in their volar skin, suggesting these models should be selected according to research focus on skin appendages.

The study found that a novel mixture of mastic gum and peppermint extract increased hair growth and gloss in C57BL/6 mice, showing potential as a botanical alternative for promoting hair health.

This study found that combining a human acellular amniotic membrane with iPSC-derived epithelial stem cells effectively repaired skin defects and promoted hair follicle formation in nude mice.

This review discusses the heterogeneity and plasticity of epithelial stem cells in skin homeostasis, wound healing, and tumorigenesis, reporting no new results but emphasizing the need for further exploration of key regulatory mechanisms.

This study found that abolishing H3K27me3 in mouse skin by targeting Ezh2 and Ezh1 affects hair follicle development and epidermal behavior, revealing functional differences between these tissues.

In this study, CTCF was found to play essential roles in epidermal differentiation and skin barrier formation, simultaneously acting as a suppressor of epithelial inflammatory responses in mouse skin.

This study found that disrupting Adam10 in the epidermis led to severe skin and multi-organ abnormalities, implicating Adam10 as crucial for proper Notch signaling and skin maintenance.

This study found that the p63 transcription factor is expressed during rat epidermal development and may serve as a specific marker for keratinocyte progenitor cells.

In this study, researchers found that deleting Med1, a key epigenetic regulator in dental epithelia, led to hair growth on mouse incisors by altering enhancer landscapes and causing a switch from dental to hair lineage transcription programs.

This study found that Notch-related genes, including Notch1 and Notch2, and their ligands and regulators, have distinct patterns of expression during mouse hair vibrissa follicle development and the adult hair cycle.

This study found that ILK deficiency disrupts hair follicle development by impairing cell polarity and laminin-511 assembly, but these defects can be partially reversed with exogenous laminin-511.

This review discusses the development of human skin with a focus on desmosomes, noting the challenges of translating animal model findings to humans due to species differences and limited human sample access.

This study found that miR-148a plays a significant role in regulating skin homeostasis and hair follicle cycling, influencing stem cell activity and development in mice.

This article reviews the role of skin appendages in wound healing and appendage regeneration, discussing cellular and molecular mechanisms but reports no new experimental findings.

The researchers reported that hair follicle germinative epidermal cells can form complex structures when associating with papilla cells in culture, unlike other types of epidermal cells.

This study found that hair follicle patterning in development may arise from a combination of epidermal prepattern signals and mesenchymal self-organisation, with fibroblast growth factor and bone morphogenetic protein activities playing key roles.

This study found that Acvr1b signaling is crucial for both hair follicle development and cycling in mice, with the genetic disruption leading to hair loss and a thickened epidermis.