research Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin
PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
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research Transcriptome Analyses of Reprogrammed Feather/Scale Chimeric Explants Revealed Co-Expressed Epithelial Gene Networks During Organ Specification
Key genes can rewire networks, changing skin appendage types.
research Thyroid Hormone Action on Skin
Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.
research Lineage Analysis of Epidermal Stem Cells
Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
research Transcriptome Profiling of Human Follicle Dermal Papilla Cells in Response to Porphyra-334 Treatment by RNA-Seq
Porphyra-334 may help reduce wrinkles and promote hair growth.
research Antigen Presenting Cells in the Skin of a Patient with Hair Loss and Systemic Lupus Erythematosus
Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.
research Redox-Directed Interventions Targeting Skin Photodamage
Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.
research Ameliorative Effect of Tranexamic Acid on Physiological Skin Aging and Its Sex Difference in Mice
Tranexamic acid reduces skin aging more in female mice.
research Sphingolipid Metabolism Orchestrates the Establishment of the Adult Hair Follicle Stem Cell Niche to Control Skin Homeostasis
A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
research Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
research Advances in the Management of Cutaneous Toxicities of Targeted Therapies
Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.
research Live Imaging of Stem Cells: Answering Old Questions and Raising New Ones
Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
research An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation
Estrogen affects hair growth and skin cell multiplication.
research Eph/Ephrin Signaling in Epidermal Differentiation and Disease
Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
research Genome-Wide Association Study of Skin Complex Diseases
Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
research Epidermal Expression of Receptor for Advanced Glycation End Products (RAGE) Is Related to Inflammation and Apoptosis in Human Skin
Skin RAGE levels are linked to inflammation and cell death.
research Age-Associated Inflammation Connects RAS-Induced Senescence to Stem Cell Dysfunction and Epidermal Malignancy
Older skin has higher cancer risk due to inflammation and stem cell issues.
research TCDD-Induced Activation of Aryl Hydrocarbon Receptor Regulates the Skin Stem Cell Population
TCDD disrupts skin stem cells, causing skin issues like chloracne.
research Histopathological and Ultrastructural Study of Ectodermal Dysplasia/Skin Fragility Syndrome
The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.
research Thy1 Marks a Distinct Population of Slow-Cycling Stem Cells in the Mouse Epidermis
A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.
research Hair Follicle-Targeted Delivery of Azelaic Acid Micro/Nanocrystals Promotes the Treatment of Acne Vulgaris
Azelaic acid micro/nanocrystals, especially with ultrasound and salicylic acid, greatly improve acne treatment.
research Clinical and Histopathological Features and Potential Pathological Mechanisms of Skin Lesions in COVID-19: Review of the Literature
COVID-19 can cause various skin lesions, which may result from the virus and immune response, and are not directly linked to illness severity.
research Hair Follicle Morphogenesis and Epidermal Homeostasis in We/We Wal/Wal Mice with Postnatal Alopecia
The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.
research Immunopathology of the Human Hair Follicle
The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.
research Inherited Ichthyoses: Generalized Mendelian Disorders of Cornification
Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.
research Physiologic Skin Changes Associated With Pregnancy
Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.
research New Insights Into Inflammatory Memory of Epidermal Stem Cells
Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
research Characterization of CD4+ Stem Cells of the Skin and Their Role in Skin Homeostasis and Tumorigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Cell Death as an Architect of Adult Skin Stem Cell Niches
Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
research Biotin Is Required for Zinc Homeostasis in the Skin
Biotin is important for keeping zinc levels balanced in the skin and its lack can cause hair loss.