January 2008 in “Journal of The American Academy of Dermatology” Hair loss affects 20% of people, more in men and those over 35, and is often associated with a sensitive scalp.
January 2008 in “Yearbook of Dermatology and Dermatologic Surgery” One type of progenitor cell can maintain normal skin in mice.
January 2008 in “Chinese bulletin of Life sciences” Epidermal stem cells help renew skin and regenerate hair follicles.
August 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Overexpression of a specific receptor in mice skin causes skin thinning, early skin barrier formation, eye issues, and hair loss.
January 2006 in “Elsevier eBooks” Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.
September 2005 in “CRC Press eBooks” Vitamin D is important for skin cell growth and health, and its active form and receptor play key roles in skin and hair processes.
January 2001 in “Nishi Nihon hifuka” The document concluded that there are differences in hair growth cycles and skin cell turnover rates, which can be measured with electronic equipment.
The estrogen receptor pathway controls hair growth cycles and affects skin cell growth.
December 2022 in “Stem Cells and Development” Exosomes from stem cells help improve nerve repair in rats.
March 2023 in “Epilepsia” Trilostane may help delay epilepsy development by increasing certain brain chemicals.
October 2020 in “Journal of Pharmaceutical Sciences” Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.
M-CSF-stimulated myeloid cells can turn into skin cells and help heal wounds and regrow hair.
May 2022 in “Endocrine Abstracts” Finasteride may cause sexual dysfunction by reducing epinephrine levels.
January 2022 in “Journal of Healthcare Sciences” Male Androgenetic Alopecia, a common hair loss in men, can be slowed and partially restored with treatments like minoxidil and finasteride, or hair transplantation. Serenoa repens may be an alternative treatment. More research is needed for new treatments.
Myeloid cells can turn into skin and hair cells to help heal wounds.
Androgenetic alopecia is more common in male Chinese adolescents and linked to rosacea, but doesn't affect quality of life.
April 2020 in “The FASEB Journal” Finasteride may cause lasting sexual issues by altering specific genes in human cells.
January 2019 in “The Chinese Journal of Dermatovenereology” April 2018 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei” All types of alopecia involve hair follicle damage, especially in alopecia areata.
November 2016 in “Hair transplant forum international” The conclusion is that more research is needed to understand if the drug finasteride causes Post-Finasteride Syndrome or if it's due to individual genetic makeup.
300 citations,
August 2012 in “Seminars in Cell & Developmental Biology” The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
177 citations,
November 2002 in “British journal of dermatology/British journal of dermatology, Supplement” Transplantation is effective for stable leucoderma but not for progressive, widespread vitiligo vulgaris.
170 citations,
November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.
116 citations,
August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
114 citations,
October 1996 in “Dermatologic clinics” Hair loss is mainly caused by hormones, autoimmune issues, and chemotherapy, and needs more research for treatments.
106 citations,
March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
105 citations,
February 2017 in “British Journal of Dermatology” Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.
103 citations,
October 2003 in “Birth Defects Research” Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
101 citations,
June 2005 in “Journal of The American Academy of Dermatology” Very few people experience increased hair growth after laser hair removal, especially those with darker skin and black hair.
85 citations,
July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.