43 citations
,
July 2013 in “Pharmacological reviews” This article reviews the pharmacology of bimatoprost and prostamide F2α, highlighting bimatoprost's therapeutic applications in glaucoma, hair growth, and potential fat reduction, without reporting new experimental results.
42 citations
,
January 2019 in “Frontiers in Immunology” This study identified diltiazem, a calcium channel blocker for hypertension, as a promising repurposed treatment for influenza, enhancing antiviral efficacy when combined with oseltamivir.
39 citations
,
April 2011 in “Recent Patents on Drug Delivery & Formulation” This review discusses various applications of nanoemulsions in drug delivery and reports no new clinical results; it highlights the patents that cover these applications.
38 citations
,
June 2019 in “International Journal of Molecular Sciences” This review discusses the potential role of extracellular vesicles in modulating hair follicle dynamics and reports no new clinical results; future investigations may inform treatment strategies for skin disorders.
31 citations
,
October 2010 in “Progress in lipid research” This review discusses the role of LPA(3) in embryo implantation and its genetic connection with prostaglandin signaling, but reports no new clinical results.
29 citations
,
January 2016 in “Annals of dermatology/Annals of Dermatology” This study found that arachidonic acid may promote hair growth by enhancing dermal papilla cell function and stimulating the anagen phase in C57BL/6 mice.
28 citations
,
October 2019 in “Seminars in Cell & Developmental Biology” This article discusses the advances in understanding wound-induced hair follicle neogenesis (WIHN) and highlights the roles of specific signaling pathways and cellular plasticity, noting no clinical results but suggesting potential areas for further research.
28 citations
,
January 2018 in “Biochemical Society Transactions” This review explores the role of fatty acids and bioactive lipid mediators in skin health and suggests targeting this metabolic network to control inflammation and improve skin conditions, but it reports no new findings.
28 citations
,
March 2014 in “International Journal of Nanomedicine” This study developed lipid nanoparticles for delivering minoxidil and finasteride to the dermis and hair follicles, showing stability and a desired prolonged release, though with low skin penetration levels.
23 citations
,
June 2006 in “Journal of Investigative Dermatology” Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.
23 citations
,
January 2018 in “Elsevier eBooks” This chapter reviews formulation principles for creating cosmetic nanoemulsions and applications targeting skin and hair care, but does not present new experimental results.
22 citations
,
October 2012 in “Cell Transplantation” This study found that adding Wnt-10b to the culture medium of dermal papilla cells maintained their ability to induce hair follicles over 100 days in vitro.
21 citations
,
July 2017 in “Journal of Cosmetic and Laser Therapy” This review discusses the research and development of vesicular carriers to enhance the delivery and effectiveness of active ingredients in cosmetic products, reporting no new clinical results.
16 citations
,
January 2018 in “Biochemical and Biophysical Research Communications” In this study, researchers established five new immortalized human dermal papilla cell lines from a male with androgenetic alopecia, which may serve as valuable tools for hair research.
14 citations
,
July 2021 in “Reviews in endocrine and metabolic disorders” This study explores how SARS-CoV-2 interacts with endocrine organs and highlights specific endocrine molecules that help explain the progression and outcomes of COVID-19, especially in patients with certain metabolic conditions.
13 citations
,
March 2021 in “British Journal of Pharmacology” This study found that KY19382 can effectively promote hair regeneration and follicle neogenesis in mice and human hair models by activating Wnt/β-catenin signalling, suggesting potential use for alopecia treatment.
13 citations
,
July 2019 in “Journal of Dermatological Science” This study suggests that 3D spheroid cultivation of dermal papilla cells can restore their hair-inductive capabilities, which are lost in 2D-cultured cells.
12 citations
,
December 2021 in “Aging” This study demonstrated that a new non-invasive method for collecting and analyzing mouse hair follicles could replace traditional biopsy methods, providing advantages for translational research and routine applications.
12 citations
,
February 2014 in “Recent Patents on Inflammation & Allergy Drug Discovery” This article reviews various aspects of shampoos, including preparation methods and commercial value, but reports no new experimental results, instead focusing on patents and product evaluation criteria.
10 citations
,
January 2007 in “Dermatology” This study reported higher levels of certain proteins, such as DAX-1, SRY, and WT-1, in the bald scalp of patients with androgenetic alopecia.
9 citations
,
November 2019 in “Scientific reports” This study isolated a bioactive peptide from Trapa japonica fruit and found that it may protect human dermal papilla cells from DHT-induced stress, suggesting potential for biomedical applications.
9 citations
,
January 2014 in “Medical Hypotheses” This article discusses the hypothesis that mechanisms driving androgenic alopecia may reduce the risk and proliferation of prostate cancer by increasing prostaglandin D2 levels but presents no new clinical findings.
9 citations
,
March 2019 in “Scientific reports” This study found that transient non-lethal levels of endogenous ROS in cultured human hair follicles promoted entry into the growth phase by activating the hair follicle stem cell niche.
8 citations
,
October 2018 in “Applied sciences” This study found that alginate spheres maintain dermal papilla cells in a dormant state with increased trichogenecity, suggesting potential benefits for cell therapy in androgenic alopecia.
7 citations
,
July 2018 in “Biological & Pharmaceutical Bulletin” This study found that Phyllanthus urinaria extract displayed significant anti-alopecia properties in a mouse model, showing potential as an anti-5α-reductase agent for androgenic hair loss.
6 citations
,
March 2021 in “Cytotechnology” This review examines recent findings on COVID-19 pneumonia treatment using mesenchymal stem cells and reports no new clinical results; the authors highlight MSCs' potential due to their immunomodulatory and tissue-regenerative properties.
6 citations
,
April 2022 in “Cellular and Molecular Life Sciences” This study reports that a new protocol using Angio PRP improved wound healing in mice by enhancing key healing processes and regulating inflammation, suggesting potential for clinical advancements.
5 citations
,
October 2025 in “International Journal of Nanomedicine” This review discusses the role of traditional Chinese medicine and bioactive materials in chronic wound healing and reports no new clinical results.
5 citations
,
December 2004 in “Dermatology” This review describes two cases of young women with primary amenorrhea and hyperandrogenemia, suggesting that adrenal tumors should be considered in patients with significantly elevated circulating testosterone levels.
4 citations
,
May 2021 in “Lasers in Surgery and Medicine” This study observed that adding low-level light therapy with the GentleWaves® device to Minoxidil significantly boosted hair regrowth in men with androgenetic alopecia by reducing scalp inflammation.