Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study identified specific profiles and courses of adverse events associated with boron neutron capture therapy for head and neck cancer, suggesting differences based on the beam incidence site.

This study identified KRT82 as a significant Alopecia Areata risk gene, finding that rare damaging variants are linked to elevated immune cell infiltration around hair follicles in affected individuals.

The combination of gemcitabine and vinorelbine is effective and safe for treating elderly patients with advanced breast cancer previously treated with anthracyclines and taxanes.

This review evaluates therapies for hyperandrogenism, highlighting cyproterone acetate as the preferred treatment due to its potency and tolerability in managing symptoms in women.

This study developed a caffeine-loaded solid lipid nanoparticle gel, observing significant reduction in subcutaneous fat tissue thickness in histological tests compared to an untreated group, suggesting it could effectively treat cellulite as a promising nanocosmeceutical gel.

This study describes three new cases of MCOPS6 with BMP4 variants, noting expanded phenotypic variability but no clinically apparent microphthalmia in these individuals, which is commonly reported in the disorder.

This review discusses various treatment challenges and toxicities in patients with relapsed follicular lymphoma and suggests that novel therapies could improve outcomes by reducing exposure to harmful chemotherapy cycles.

This study observed that an 8-session mindfulness-based cognitive therapy reduced social anxiety and improved wellbeing in some individuals with alopecia areata, though effectiveness may depend on regular mindfulness practice.

This case report describes the successful surgical removal of a trichobezoar in an 8-year-old girl, which extended from her stomach into the duodenum.

This study characterized hair from a patient with a ribosomopathy and identified distinct differences, including reduced hair thickness and lipid content, compared to family members.

The drug TGU was ineffective against small cell lung cancer and caused significant bone marrow suppression.

This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.

This study found that mutations in the TULP3 gene are associated with progressive degeneration of the liver, kidney, and heart in adults, highlighting the importance of early detection and management.

This case report documents the first successful management of accidental minoxidil toxicosis in a dog, resulting in full recovery after treatment with supportive care, including medications for blood pressure and potential toxicity mitigation.

This review discusses the role of glucocorticoids in treating severe inflammatory disorders and highlights their potential adverse effects, recommending dosage management to minimize these risks; no new clinical results are reported.

This review suggests that dihydrotestosterone pretreatment may improve cosmetic outcomes in hypospadias repair, but more randomized trials are needed to determine its effectiveness due to currently limited evidence.

This study found that greater root surface area due to root hairs contributed to better growth and zinc uptake of wild-type barley compared to its root-hairless mutant in zinc-deficient soil.

This report describes three cases of hypertrichosis lanuginosa acquisita occurring after cytotoxic chemotherapy for cancer, suggesting a possible relationship which is discussed alongside a review of existing literature.

This study concluded that the GIANT brain atlas, which integrates genetic and neuroanatomical variations, provides a more accurate representation of brain structure than traditional neuroanatomical atlases, allowing for better exploration of genetic influences on the brain.

This study discusses the epithelial-immune microenvironment in chronic skin diseases, such as psoriasis and atopic dermatitis, and highlights current and future treatment strategies targeting inflammatory loops within these diseases.

This source reports that trastuzumab deruxtecan improves outcomes in HER2-positive and HER2-low metastatic breast cancer, emphasizing the need for careful adverse event monitoring, particularly for interstitial lung disease, and managing emetic risk to maximize benefits.

This review suggests that mesenchymal stem cells' therapeutic effects might be due to bioactive substances they release, rather than the cells themselves, highlighting the potential of the MSC secretome as a novel, cell-free therapeutic approach.

This study found a recurrent nonsense mutation in the HR gene linked to atrichia with papular lesions in two Kashmiri families, suggesting whole exome sequencing as an efficient method for diagnosis and genetic counseling.

In this study, aleglitazar and its metabolite M6 were evaluated for safety in non-clinical settings, revealing organ-targeting effects common to PPAR agonists but no significant tumor increase in rat carcinogenicity studies, supporting progression to Phase 3 clinical trials.

This paper reviews the potential of Ayurvedic herbs like ginger, garlic, and turmeric to reduce the side effects of cancer therapies and enhance patient wellbeing but reports no new experimental findings.

The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.

This review examines the traditional uses and biological activities of Glycyrrhiza glabra in Ayurveda, but reports no new clinical results; the authors identify a gap in evidence supporting its medicinal potential.

In this study, researchers found that a PER3 gene SNP may be pathogenic for a new subtype of dyschromatosis universalis hereditaria, especially when combined with a SASH1 mutation.

This case report discusses a 5-year-old Persian cat with feline eosinophilic granuloma complex, which responded positively to prednisone and topical corticosteroids, eliminating itching and promoting fur regrowth without relapse.

Among families with pediatric brain disease, this study identified over 200 novel genetic causes, revealing potential treatment points using drug repurposing or nutritional supplementation.